Descripción del proyecto
Virtual Physiological Human
Cardiovascular disease (CVD) has a significant impact on the European society in terms of mortality, morbidity and allied healthcare costs. The opportunity of multi-scale modelling spanning, sub-cellular level up to whole heart is to improve CVD outcomes by providing a consistent, biophysically-based framework for the integration of the huge amount of fragmented and inhomogeneous data currently available. However, multi-scale models have not yet been translated into clinical environments mainly due to the difficulty of personalising biophysical models. The challenge of the euHeart project is to directly address this need by combining novel ICT technologies with integrative multi-scale computational models of the heart in clinical environments to improve diagnosis, treatment planning and interventions for CVD.
To meet this challenge we will bring together leading European physiological modelling and cardiac groups to develop, integrate and clinically validate patient-specific computational models of the cardiac physiology and disease-related processes. The main outcome of euHeart will be an open source framework for the description and representation of normal and pathological multi-scale and multi-physics cardiovascular models, using the international encoding standards. In addition, a library of innovative tools for the execution of the biophysical simulations, the personalisation of the models and the automated analysis of multi-modal images are developed.
Evidence of clinical benefit will be collected to quantify potential impact for a number of significant CVD's namely, heart failure, cardiac rhythm disorder, coronary artery disease and valvular and aortic diseases. Each of the selected clinical applications provides a complementary focus for the resulting integrated model of cardiac fluid-electro-mechanical function. The consortium contains a mix of academic leadership, clinical sites, and industrial partners ensuring exploitation of the wealth of models
Ámbito científico
Convocatoria de propuestas
FP7-ICT-2007-2
Consulte otros proyectos de esta convocatoria
Régimen de financiación
CP - Collaborative project (generic)Coordinador
20099 HAMBURG
Alemania
Ver en el mapa
Participantes (20)
1930 ZAVENTEM
Ver en el mapa
76131 Karlsruhe
Ver en el mapa
La participación finalizó
69120 Heidelberg
Ver en el mapa
La participación finalizó
76131 KARLSRUHE
Ver en el mapa
La participación finalizó
64404 BICKENBACH
Ver en el mapa
69120 Heidelberg
Ver en el mapa
12247 BERLIN
Ver en el mapa
28046 MADRID
Ver en el mapa
La participación finalizó
28040 MADRID
Ver en el mapa
28050 Madrid
Ver en el mapa
08002 Barcelona
Ver en el mapa
75654 Paris
Ver en el mapa
78153 Le Chesnay Cedex
Ver en el mapa
1105AZ Amsterdam
Ver en el mapa
5684 PC Best
Ver en el mapa
5611 ZS Eindhoven
Ver en el mapa
OX1 2JD Oxford
Ver en el mapa
WC2R 2LS London
Ver en el mapa
S10 2TN Sheffield
Ver en el mapa
35065 RENNES CEDEX
Ver en el mapa