Objective The mouse shows great similarities in development, physiology and biochemistry to humans, which makes it a key model for research into human disease. The major challenges for mouse functional genomics in the 21st century are to:1) Develop a series of mutant alleles for every gene in the mouse genome2) Determine the phenotypic consequences of each mutation3) Identify mouse models for the complete disease spectrum in humansTo exploit this emerging resource, mouse models must be preserved and made available to the European biomedical research community. Building on EMMA's previous achievements as the primary mouse repository in Europe, EMMAservice aims to meet the future challenges presented by archiving and disseminating mouse models in the ERA as follows:- Archiving of 1224 new mouse mutant lines in support of individual depositors and also European mouse genetics programmes- Support of eligible customers with free of charge Transnational Access for up to 20% of requested mouse resources.- Technology development will underpin the archiving and distribution efforts by advancing current sperm freezing technology- Training courses will promote the shipment of frozen germplasm rather than live mice- EMMA informatics will support user services by setting new standards for user friendly accession of EMMA services, extensive data curation and cross referencing with other mouse database resources- Outreach efforts to attract users will be widened and addressed at the translational research communityEMMAservice will contribute significantly to the development of a world leading repository and European capacity in mouse disease model archiving and distribution, supporting the needs of the wider European biomedical research community. The emerging mouse mutant and associated data resources will offer the opportunity to decipher molecular disease mechanisms and may, in some instances, provide the foundation for the development of diagnostic, prognostic and therapeutic strategies. Fields of science natural sciencesbiological sciencesbiochemistrynatural sciencescomputer and information sciencesdatabasesnatural sciencesbiological sciencesgeneticsmutationmedical and health sciencesbasic medicinephysiologynatural sciencesbiological sciencesgeneticsgenomes Keywords Cryopreservation disease models functional genomics mouse mutants mouse repository Programme(s) FP7-INFRASTRUCTURES - Specific Programme "Capacities": Research infrastructures Topic(s) INFRA-2008-1.1.1 - Bottom-up approach: Integrating Activities in all scientific and technological fields Call for proposal FP7-INFRASTRUCTURES-2008-1 See other projects for this call Funding Scheme CP-CSA-Infra - Combination of CP and CSA Coordinator CONSIGLIO NAZIONALE DELLE RICERCHE Address Piazzale aldo moro 7 00185 Roma Italy See on map Region Centro (IT) Lazio Roma Activity type Research Organisations Administrative Contact Glauco Tocchini-Valentini (Prof.) Links Contact the organisation Opens in new window Website Opens in new window EU contribution € 786 894,46 Participants (9) Sort alphabetically Sort by EU Contribution Expand all Collapse all CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS France EU contribution € 1 258 199,60 Address Rue michel ange 3 75794 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Administrative Contact Josette Roger (Ms.) Links Contact the organisation Opens in new window Website Opens in new window MEDICAL RESEARCH COUNCIL United Kingdom EU contribution € 1 048 622,75 Address 20 park crescent W1B 1AL London See on map Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Administrative Contact Hilary Gates (Dr.) Links Contact the organisation Opens in new window Website Opens in new window KAROLINSKA INSTITUTET Sweden EU contribution € 306 008,00 Address Nobels vag 5 17177 Stockholm See on map Region Östra Sverige Stockholm Stockholms län Activity type Higher or Secondary Education Establishments Administrative Contact Riitta Ljungström (Ms.) Links Contact the organisation Opens in new window Website Opens in new window FUNDACAO CALOUSTE GULBENKIAN Portugal EU contribution € 452 490,00 Address Avenida berna 45a 1067-001 Lisboa See on map Region Continente Área Metropolitana de Lisboa Área Metropolitana de Lisboa Activity type Research Organisations Administrative Contact Jose Mario Leite (Dr.) Links Contact the organisation Opens in new window Website Opens in new window HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH Germany EU contribution € 1 591 113,55 Address Ingolstadter landstrasse 1 85764 Neuherberg See on map Region Bayern Oberbayern München, Landkreis Activity type Research Organisations Administrative Contact Jürgen Ertel (Dr.) Links Contact the organisation Opens in new window Website Opens in new window EUROPEAN MOLECULAR BIOLOGY LABORATORY Germany EU contribution € 650 559,60 Address Meyerhofstrasse 1 69117 Heidelberg See on map Region Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis Activity type Research Organisations Administrative Contact Keith Williamson (Mr.) Links Contact the organisation Opens in new window Website Opens in new window CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE France EU contribution € 552 600,80 Address Rue laurent fries 1 67404 Illkirch graffenstaden See on map Region Grand Est Alsace Bas-Rhin Activity type Research Organisations Administrative Contact Katell Schaeffer (Ms.) Links Contact the organisation Opens in new window Website Opens in new window GENOME RESEARCH LIMITED United Kingdom EU contribution € 672 411,59 Address The gibbs building, euston road 215 NW1 2BE London See on map Region London Inner London — West Camden and City of London Activity type Research Organisations Administrative Contact David Neil Davison (Mr.) Links Contact the organisation Opens in new window Website Opens in new window AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS Spain EU contribution € 681 099,65 Address Calle serrano 117 28006 Madrid See on map Region Comunidad de Madrid Comunidad de Madrid Madrid Activity type Research Organisations Administrative Contact Maria Del Mar Garcia (Ms.) Links Contact the organisation Opens in new window Website Opens in new window
