Objective Persistent infections such as HIV, tuberculosis´(TB) in humans and para-tuberculosis (ParaTB)-, mycoplasma- and Haemophilus-infections in farm animals are global health problems of immense social and economic importance . HIV-1 affects about 40 million people and M. tuberculosis infection is even higher world-wide. Co-infection with M. tuberculosis is estimated in about one-third of HIV-1 infected subjects. Globally, there are more than 14 million persons dually infected with TB and HIV. Drug resistance to HIV-treatment and appearance of multiple-drug resistance (MDR) and off late of Extra-Drug Resistance (XDR) strains of M. tuberculosis , the causative agent of human TB is steadily leading to a hopeless situation as far as therapy is concerned. To make things worse, there is no effective vaccine available against the persistent infections addresses in this proposal. The four SME members of this consortium with complimentary areas of research and business activities, LIONEX (in TB), Prionics (in ParaTB) , Vichem (in HIV) and IVD (in pig infections) are dedicated to solving the problems of the persistent infections mentioned above by employing novel strategies of product development for diagnosis, prevention and control of these global diseases by outsourcing demanding but feasible work to internationally known research organisations (RTDP) with highly positive track record. The SMEs alone cannot perform the outsourced work but shall validate and exploit the results provided by the RTDPs. Our novel but realistic objectives are: 1. To develop new drug candidates for drug resistant persistent infections (HIV and TB) 2. To identify and isolate novel antigens for the diagnosis of TB, ParaTB and infections in pigs 3. To identify antigens suitable for vaccine development for these persistent infections 4. To develop marketable, improved diagnostic products within a period of three years Fields of science medical and health sciencesbasic medicinepharmacology and pharmacydrug discoverymedical and health scienceshealth sciencesinfectious diseasesRNA virusesHIVmedical and health sciencesclinical medicinepneumologytuberculosismedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsvaccinesmedical and health sciencesbasic medicinepharmacology and pharmacydrug resistancemultidrug resistance Programme(s) FP7-SME - Specific Programme "Capacities": Research for the benefit of SMEs Topic(s) SME-1 - Research for SMEs Call for proposal FP7-SME-2008-1 See other projects for this call Funding Scheme BSG-SME - Research for SMEs Coordinator LIONEX GMBH Address Salzdahlumer strasse 196 38126 Braunschweig Germany See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) projects.administrative_contact Mahavir Singh (Prof.) Links Contact the organisation Opens in new window Website Opens in new window EU contribution € 533 984,00 Participants (11) Sort alphabetically Sort by EU Contribution Expand all Collapse all VICHEM CHEMIE KUTATO KORLATOLT FELELOSSEGU TARSASAG Hungary EU contribution € 100 410,00 Address Viola utca 2 8200 Veszprem See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) projects.administrative_contact György Kéri (Prof.) Links Contact the organisation Opens in new window Website Opens in new window PRIONICS AG Switzerland EU contribution € 359 000,00 Address Wagistrasse 27 a 8952 Schlieren See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) projects.administrative_contact Alex Raeber (Dr.) Links Contact the organisation Opens in new window Website Opens in new window IVD GESELLSCHAFT FUR INNOVATIVE VETERINARDIAGNOSTIK GMBH Germany EU contribution € 276 700,00 Address Heisterbergallee 12 30453 Hannover See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) projects.administrative_contact Gerald-F. Gerlach (Prof.) Links Contact the organisation Opens in new window Website Opens in new window HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH Germany EU contribution € 8 160,00 Address Inhoffenstrasse 7 38124 Braunschweig See on map Activity type Research Organisations projects.administrative_contact Michael Strätz (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Food and Environment Research Agency GB EU contribution € 11 200,00 Address Area 1a, nobel house, smith square 17 SW1P 3JR London See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) projects.administrative_contact Lucinda Cranham (Ms.) Links Contact the organisation Opens in new window Website Opens in new window KAROLINSKA INSTITUTET Sweden EU contribution € 9 200,00 Address Nobels vag 5 17177 Stockholm See on map Activity type Higher or Secondary Education Establishments projects.administrative_contact Jill Blomstrand (Ms.) Links Contact the organisation Opens in new window Website Opens in new window INSTITUT DE INVESTIGACIO EN CIENCIES DE LA SALUT GERMANS TRIAS I PUJOL Spain EU contribution € 4 440,00 Address Ctra de canyet s/n 08916 Badalona barcelona See on map Activity type Research Organisations projects.administrative_contact Pere-Joan Cardona Iglesias (Prof.) Links Contact the organisation Opens in new window UNIVERSITA DEGLI STUDI DI FIRENZE Italy EU contribution € 5 696,00 Address Piazza san marco 4 50121 Florence See on map Activity type Higher or Secondary Education Establishments projects.administrative_contact Sergio Romagnani (Prof.) Links Contact the organisation Opens in new window Website Opens in new window PRINS LEOPOLD INSTITUUT VOOR TROPISCHE GENEESKUNDE Belgium EU contribution € 11 200,00 Address Nationalestraat 155 2000 Antwerpen See on map Activity type Higher or Secondary Education Establishments projects.administrative_contact Jozef Van Lint (Mr.) Links Contact the organisation Opens in new window Website Opens in new window TECHNISCHE UNIVERSITAT CLAUSTHAL Germany EU contribution € 0,00 Address Adolph romer strasse 2a 38678 Clausthal zellerfeld See on map Activity type Higher or Secondary Education Establishments projects.administrative_contact Heike Schroeder (Dr.) Links Contact the organisation Opens in new window Website Opens in new window STIFTUNG TIERAERZTLICHE HOCHSCHULE HANNOVER Germany EU contribution € 0,00 Address Bunteweg 2 30559 Hannover See on map Activity type Higher or Secondary Education Establishments projects.administrative_contact Peter Joppe (Mr.) Links Contact the organisation Opens in new window Website Opens in new window