IMPROVED RETROGRADE LENTIVIRAL VECTORS FOR GENE THERAPY IN MOTOR NEURON DISEASES

Project Information

IRLVGTMND

Grant agreement ID: 233147

Project closed

Start date 1 April 2009

End date 31 August 2014

Funded under

• Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Total cost € 2 000 000,00

EU contribution € 2 000 000,00

Coordinated by

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Publications via OpenAIRE (18)

Development of novel targeted lentiviral vectors for gene therapy of motor neuron diseases

Author(s): Eleftheriadou, Ioanna
Published in: Imperial College London 2013
Permanent ID: Digital Object Identifier:10.25560/27243; Microsoft Academic Graph Identifier:2295055488; Handle:10044/1/27243

Specific Retrograde Transduction of Spinal Motor Neurons Using Lentiviral Vectors Targeted to Presynaptic NMJ Receptors

Author(s): Antonio Trabalza; Ioanna Eleftheriadou; Nicholas D. Mazarakis; K Gharun; K Gharun; Stuart M. Ellison
Published in: Elsevier BVEleftheriadou , I , Trabalza , A , Ellison , S M , Gharun , K & Mazarakis , N D 2014 , ' Specific retrograde transduction of spinal motor neurons using lentiviral vectors targeted to presynaptic NMJ receptors ' , Molecular therapy : the journal of the American Society of Gene Therapy , vol. 22 , no. 7 , pp. 1285-1298 . https://doi.org/10.1038/mt.2014.49 2014
Permanent ID: Digital Object Identifier:10.1038/mt.2014.49; PubMed ID:24670531; PubMed Central ID:PMC4089010; Microsoft Academic Graph Identifier:2050379618

Rabies Virus Envelope Glycoprotein Targets Lentiviral Vectors to the Axonal Retrograde Pathway in Motor Neurons

Author(s): James N. Hislop; Tarin A. Islam; Ioanna Eleftheriadou; David C. J. Carpentier; Antonio Trabalza; Michael Parkinson; Giampietro Schiavo; Nicholas D. Mazarakis
Published in: Elsevier BVJournal of Biological Chemistry 2014
Permanent ID: Digital Object Identifier:10.1074/jbc.m114.549980; PubMed ID:24753246; PubMed Central ID:PMC4047386; Microsoft Academic Graph Identifier:2032241863

Rabies virus glycoprotein targets lentiviral vectors for retrograde vesicular transport in motor neurons

Author(s): Tarin A. Islam; James N Hislop; David CJ Carpentier; I Eleftheriadou; Antonio Trabalza; Nicholas D Mazarakis

Development of Novel Targeted Lentiviral Vectors for Gene Therapy of Motor Neuron Diseases

Author(s): Ioanna Eleftheriadou, Antonio Trabalza, Stuart M Ellison; Nicholas D Mazarakis

Enhanced pseudotyping efficiency of HIV-1 lentiviral vectors by a rabies/vesicular stomatitis virus chimeric envelope glycoprotein

Author(s): David C. J. Carpentier; K Vevis; K Vevis; Antonio Trabalza; Nicholas D. Mazarakis; Stuart M. Ellison; Christos Georgiadis; R I Asfahani; R I Asfahani
Published in: Springer Science and Business Media LLCCarpentier , D C J , Vevis , K , Trabalza , A , Georgiadis , C , Ellison , S M , Asfahani , R I & Mazarakis , N D 2012 , ' Enhanced pseudotyping efficiency of HIV-1 lentiviral vectors by a rabies/vesicular stomatitis virus chimeric envelope glycoprotein ' , Gene Therapy , vol. 19 , no. 7 , pp. 761-74 . https://doi.org/10.1038/gt.2011.124 2011
Permanent ID: Digital Object Identifier:10.1038/gt.2011.124; PubMed ID:21900965; Microsoft Academic Graph Identifier:1974124274

Thy1.1, p75NTR or CAR receptor targeting by lentiviral vectors leads to retrograde transport and transduction of spinal motor neurons following peripheral delivery

Author(s): I Eleftheriadou; A Trabalza; S M Ellison; N D Mazarakis

Lentiviral Vectors for Gene Delivery to the Nervous System

Author(s): Ioanna Eleftheriadou; Nicholas D. Mazarakis
Published in: Springer New YorkNeuromethods 2015
Permanent ID: Digital Object Identifier:10.1007/978-1-4939-2306-9_2; Microsoft Academic Graph Identifier:2486044450

) Gene Transfer to motor neurons with novel targeted lentiviral vectors.

Author(s): I Eleftheriadou; A Trabalza; S M Ellison; N D Mazarakis

Enhanced CNS transduction with lentiviral vectors pseudotyped with chimeric envelope glycoproteins

Author(s): Antonio Trabalza; Argyro Sgourou; Ting-Yi Liao; Ioanna Eleftheriadou; Petros Patsali Heyne Lee & Nicholas D. Mazarakis

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