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Content archived on 2024-05-29

Self-Assembly of Bio-Nanochips

Objective

The current proposal is devoted to the design, synthesis and investigation of chemical and physical properties of 2 2 grid-type complexes bearing biological residues, such as amino-acids, oligopeptides, nucleosides, oligonucleosides, carbohydrates or long aliphatic chains.

The project involves the following specific objectives:

- Design and synthesis of functionalized hydrazone-based ligands with side-chains bearing biological residues: amino-acids, oligopeptides, nucleosides, oligonucleosides, carbohydrate s or long aliphatic chains.

- Self-assembly of these hydrazone-based ligands with metal ions presenting preference for octahedral stereochemistry to yield cationic 2 2 grid-type complexes presenting 4, 8 or 12 side-chains.

- Self-assembly of hydrazone-base d ligands with bis(pyridyl)pyridazine ligands and metal ions showing a preference for penta-coordination in order to obtain 2 2 grid presenting 2 side-chains on one single face.

- Investigation of the capacity of biorecognition between 2 2 metallo-grid presenting 4 side-chains bearing a specific oligonucleotides sequence (codonC) and the complementary oligonucleotides sequence (anticodonAC), or between two different 2 2 metallo-grids bearing complementary oligonucleotides sequence.

¿Insertion of 2 grid-type complexes with two long aliphatic chains on one single face in lipophilic membranes and investigation of the pH-modulation of their redox and optical properties.

Fields of science (EuroSciVoc)

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Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP6-2004-MOBILITY-5
See other projects for this call

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

EIF - Marie Curie actions-Intra-European Fellowships

Coordinator

UNIVERSITE LOUIS PASTEUR
EU contribution
No data
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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