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Chromatin diseases: from basic mechanisms to therapy

Objetivo

The scope of this ITN is to promote research and training in the field of chromatin diseases. Chromatin diseases (CD) are genetic pathologies resulting from mutations in structural components of chromatin or in enzymes that biochemically modify chromatin, altering chromatin status and thereby causing drastic effects on gene expression. CD frequency ranges from very rare to quite common pathologies; so far for the vast majority of them no treatment is as yet available. Molecular studies on these pathologies thus have a twofold value: to shed light on the intricate interplays between different levels of control of gene expression acting in the mammalian nucleus and to pave the way toward new and more effective strategies to approach the treatment of this increasing class of diseases. Our students will take advantage of the integrated approach on multilayered gene regulation, the multidisciplinary nature and the cutting-edge methodologies, which are an integral part of this proposal. We thus expect to provide a framework for the very high-level training of young researchers, receiving a strong backgrounds in molecular, cellular and developmental biology, genomics, bioinformatics, chromatin biology and epigenetics. Furthermore, they will develop expertise in many cutting edge methodologies and tools, such as imaging, high throughput gene technologies, ChIP. As a result, the ESRs will be highly competitive in performing independent research in various areas of biology and will represent a new breed of scientists trained in contemporary post-genomic biology using advanced technological tools to tackle human disease.

Convocatoria de propuestas

FP7-PEOPLE-ITN-2008
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Coordinador

CONSIGLIO NAZIONALE DELLE RICERCHE
Dirección
Piazzale Aldo Moro 7
00185 Roma
Italia

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Tipo de actividad
Research Organisations
Contacto administrativo
Antonio Baldini (Prof.)
Aportación de la UE
€ 564 827

Participantes (10)

UNIVERSITE DE LA MEDITERRANEE D'AIX-MARSEILLE II

La participación finalizó

Francia
Dirección
Boulevard Charles Livon, Jardin Du Pharo 58
13284 Marseille

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Tipo de actividad
Higher or Secondary Education Establishments
Contacto administrativo
Celine Damon (Ms.)
BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING
Grecia
Aportación de la UE
€ 371 880
Dirección
Fleming Street 34
16672 Vari-athens

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Tipo de actividad
Research Organisations
Contacto administrativo
George Kollias (Dr.)
THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom
Aportación de la UE
€ 219 751
Dirección
Trinity Lane The Old Schools
CB2 1TN Cambridge

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Tipo de actividad
Higher or Secondary Education Establishments
Contacto administrativo
Edna Murphy (Ms.)
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom
Aportación de la UE
€ 213 151
Dirección
Wellington Square University Offices
OX1 2JD Oxford

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Tipo de actividad
Higher or Secondary Education Establishments
Contacto administrativo
Lynne Hughson (Ms.)
FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE
España
Aportación de la UE
€ 380 355
Dirección
Avenida Gran Via Hospitalet 199-203
08908 L'hospitalet De Llobregat

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Tipo de actividad
Research Organisations
Contacto administrativo
Victoria Cochrane (Ms.)
UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA
Italia
Aportación de la UE
€ 212 351
Dirección
Via Universita 4
41121 Modena

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Tipo de actividad
Higher or Secondary Education Establishments
Contacto administrativo
Sebastiano Calandra Buonaura (Prof.)
UNIVERSITA DEGLI STUDI DELL'INSUBRIA
Italia
Aportación de la UE
€ 205 751
Dirección
Via Ravasi 2
21100 Varese

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Tipo de actividad
Higher or Secondary Education Establishments
Contacto administrativo
Adriana Jacona (Mr.)
UNIVERSITE D'AIX MARSEILLE
Francia
Aportación de la UE
€ 206 452
Dirección
Boulevard Charles Livon 58 Le Pharo
13284 Marseille

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Tipo de actividad
Higher or Secondary Education Establishments
Contacto administrativo
Celine Damon (Ms.)
DIAGENODE
Bélgica
Aportación de la UE
€ 200 309
Dirección
Rue Du Bois Saint Jean 3 Liege Park Science
4102 Seraing

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Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contacto administrativo
Leon Etienne (Mr.)
UCL Elizabeth Garrett Anderson Institute for Women’s Health

La participación finalizó

United Kingdom
Dirección
Gower Street
WC1E 6BT London

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Tipo de actividad
Higher or Secondary Education Establishments
Contacto administrativo
Greta Borg-Carbott (Ms.)