Objective
"During development, neuronal connectivity is initially established by genetically determined intrinsic factors, e.g. molecular cues and spontaneous activity, generating networks according to a ""best guess"" strategy. However, with the appearance of sensory organs, external inputs will refine these connections, allowing adaptation to the environment. In the Xenopus developing visual system, repetitive moving visual stimuli induce long lasting changes in the direction-sensitivity of some tectal neurons, apparently via modification of synaptic strength. However, it is still unknown how this synaptic plasticity contributes to the refinement of neural circuits for precise information processing and adjustment of animal’s behaviours. Using a multidisciplinary approach combining cutting-edge genetic engineering methods to monitor and manipulate activity of specific neurons or entire circuits, development of novel mathematical and computational methods and kinematic analyses of motor behaviours, I will investigate how sensory visual experience may affect the activity and interaction of the optic tectum neuronal circuit and motor behaviour. These experiments will contribute to our understanding of the role of sensory experience in shaping the development of neural circuits and animal behaviour. They will also shed light into the mechanisms by which the nervous system self wires, adapts, and learns. The study of these mechanisms might contribute to the design of new therapeutic treatments for developmental disorders associated with impaired nerve connections."
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences neurobiology
- medical and health sciences medical biotechnology genetic engineering
- natural sciences computer and information sciences computational science
- natural sciences biological sciences biological behavioural sciences ethology
- natural sciences computer and information sciences data science data processing
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-IRG-2008
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
75654 PARIS
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.