Objective
With the clinical drive for earlier detection of disease and minimally invasive treatment, there is a paradigm shift of imaging and therapy towards in vivo, in situ surgery. One major effort towards this goal is the translation of emerging optical diagnostic imaging and therapy techniques into minimally invasive surgery (MIS) and cancer screening. This proposal will develop a novel multimodal platform that can be deployed in flexible endoscopy and robotic assisted MIS devices. This is timely in that recently there have been advances in the optical detection of diseased tissue states and also in nanotechnology that allows photothermal therapies based on focused optical energy delivery to gold nanoparticles. The clinical integration of these two strands of research offers significant promise for optical adjuvant cancer therapies and for image-guided tissue fusion, but the study of the therapeutic effect of these techniques has been limited due to the lack of a common platform for image-guided optical follow-up of the therapy. The purpose of this proposal is to develop a programmable light source for simultaneous multimodal screening and image-guided nanoparticle-mediated thermal therapy. The platform will be validated by studying of diseases of the colon to enable detection and treatment of flat polyps that may develop into invasive cancers. As a young lecturer, Dr Elson has extensive multidisciplinary experience in laser technology, biophotonics, optical imaging, microscope technique development, minimally invasive surgery and robotic-assisted surgery. He will bring together new technology with a mix of engineering, biochemistry and biophotonics skills. The proposed work will be carried out in state-of-the-art facilities with access to the clinic for translation.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry
- medical and health sciences clinical medicine surgery
- natural sciences physical sciences optics microscopy
- medical and health sciences clinical medicine oncology
- engineering and technology medical engineering diagnostic imaging
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
ERC-2009-StG
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Host institution
SW7 2AZ London
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.