Objective EU Directive 396/2005 states that methods are needed to account for cumulative and aggregate exposure in pesticides regulation . 27% of food samples had multiple residues in the 2006 EU residue monitoring report. The Eurobarometer shows pesticides are one of the principal worries of EU consumers regarding food safety. Industry needs clear criteria to decide on large investments in product development. The central aim of the ACROPLIS project is: to develop a framework for cumulative and aggregate risk assessment of pesticides in an understandable way, accessible for all actors involved in European risk assessment and management. ACROPOLIS will: 1) study the data needs, data availability and uncertainties for cumulative exposure and effect assessment in a probabilistic risk assessment framework; 2) integrate models describing various routes of exposure into an aggregate exposure model; 3) develop new toxicological approaches for identifying possible additive or synergistic effects and developing a strategy for refinement of cumulative assessment groups; 4) integrate cumulative and aggregate risk models including uncertainty analyses in a web-based tool, including accessible data for all stakeholders; 5) improve risk assessment strategies in Europe by analysing stakeholders attitudes, by training and by discussing the new methodology in several stakeholder conferences. The project brings together the key experts and models in Europe including dietary exposure MCRA, dermal and inhalation exposure ConsExpo, user exposure EUROPOEM and UK POEM, dose-response PROAST and risk characterisation IPRA. The new integrated model will be tested in case studies with conazoles and pyrethroids and validated with biomarker and duplicate diet studies. The model software will be tested in different countries to ensure its usability at the international level. Overall ACROPOLIS will advance the scientific foundation to meet policy needs, protect EU consumers and address their concerns. Fields of science natural sciencescomputer and information sciencessoftwareengineering and technologyother engineering and technologiesfood technologyfood safetymedical and health scienceshealth sciencesnutrition Programme(s) FP7-KBBE - Specific Programme "Cooperation": Food, Agriculture and Biotechnology Topic(s) KBBE-2009-2-4-03 - Combined exposure to pesticides Call for proposal FP7-KBBE-2009-3 See other projects for this call Funding Scheme CP-FP - Small or medium-scale focused research project Coordinator RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU Address Antonie van leeuwenhoeklaan 9 3721 MA Bilthoven Netherlands See on map Region West-Nederland Utrecht Utrecht Activity type Research Organisations Administrative Contact Jacob Van Klaveren (Mr.) Links Contact the organisation Opens in new window Website Opens in new window EU contribution € 761 450,26 Participants (11) Sort alphabetically Sort by EU Contribution Expand all Collapse all ISTITUTO NAZIONALE DI RICERCA PER GLI ALIMENTI E LA NUTRIZIONE Participation ended Italy EU contribution € 0,00 Address Via ardeatina, 546 00178 Roma See on map Activity type Research Organisations Administrative Contact Aida Turrini (Dr.) Links Contact the organisation Opens in new window Food and Environment Research Agency United Kingdom EU contribution € 559 916,76 Address Area 1a, nobel house, smith square 17 SW1P 3JR London See on map Region London Inner London — West Camden and City of London Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Richard Glass (Dr.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITA DEGLI STUDI DI MILANO Italy EU contribution € 453 088,20 Address Via festa del perdono 7 20122 Milano See on map Region Nord-Ovest Lombardia Milano Activity type Higher or Secondary Education Establishments Administrative Contact Monica Gritti (Dr.) Links Contact the organisation Opens in new window Website Opens in new window CONSIGLIO PER LA RICERCA IN AGRICOLTURA E L'ANALISI DELL'ECONOMIA AGRARIA Italy EU contribution € 116 370,00 Address Via della navicella 2-4 00184 Roma See on map Region Centro (IT) Lazio Roma Activity type Research Organisations Administrative Contact Aida Turrini (Dr.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITEIT UTRECHT Netherlands EU contribution € 346 251,50 Address Heidelberglaan 8 3584 CS Utrecht See on map Region West-Nederland Utrecht Utrecht Activity type Higher or Secondary Education Establishments Administrative Contact Remco Westerink (Dr.) Links Contact the organisation Opens in new window Website Opens in new window HEALTH AND SAFETY EXECUTIVE United Kingdom EU contribution € 95 638,50 Address Merton road, redgrave court L20 7HS Bootle merseyside See on map Region North West (England) Merseyside Sefton Activity type Research Organisations Administrative Contact Paul Y. Hamey (Mr.) Links Contact the organisation Opens in new window Website Opens in new window STATNI ZDRAVOTNI USTAV Czechia EU contribution € 50 906,40 Address Srobarova 48 10042 Praha 10 See on map Region Česko Praha Hlavní město Praha Activity type Research Organisations Administrative Contact Jiri Ruprich (Dr.) Links Contact the organisation Opens in new window Website Opens in new window EUROPEAN FRESH PRODUCE ASSOCIATION AISBL Belgium EU contribution € 40 334,40 Address Rue de treves 49-51 1040 Bruxelles See on map Region Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad Activity type Other Administrative Contact Philippe Binard (Mr.) Links Contact the organisation Opens in new window Website Opens in new window LIVSMEDELSVERKET Sweden EU contribution € 102 375,00 Address Dag hammarskjolds vag 56 a 752 37 Uppsala See on map Region Östra Sverige Östra Mellansverige Uppsala län Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Administrative Contact Salomon Sand (Dr.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITEIT GENT Belgium EU contribution € 96 480,00 Address Sint pietersnieuwstraat 25 9000 Gent See on map Region Vlaams Gewest Prov. Oost-Vlaanderen Arr. Gent Activity type Higher or Secondary Education Establishments Administrative Contact Nathalie Van De Pitte (Ms.) Links Contact the organisation Opens in new window Website Opens in new window STICHTING WAGENINGEN RESEARCH Netherlands EU contribution € 372 736,98 Address Droevendaalsesteeg 4 6708 PB Wageningen See on map Region Oost-Nederland Gelderland Veluwe Activity type Research Organisations Administrative Contact A. Jansen Links Contact the organisation Opens in new window Website Opens in new window