Objective
It now appears that plants purposefully generate Reactive Oxygen Species (ROS) such as Hydrogen Peroxide (H2O2) as signalling molecules to control various processes. There is now compelling evidence that H2O2 is an important signal in plants; this has been particularly reported in the case of plant – pathogen interactions. Symbiosis between Legumes and Rhizobia is characterized by the formation of a new organ on the root able to fix atmospheric nitrogen. More recently, the involvement of ROS during the symbiotic interaction has also been highlighted where H2O2 production must contribute to the control of the establishment and/or functioning of the symbiosis, by exerting a positive effect on both partners. On the other hand, H2O2 is known to interact directly with protein thiols, leading to the formation of a sulfenic acid group (sulfenylation) which has been suggested as a widespread mechanism by which H2O2 might affect protein function. Thus, the goal of the project is to identify the model plant Medicago truncatula H2O2 targets proteins during its interaction with Sinorhizobium meliloti. The three objectives are: i) isolate specifically the sulfenylated proteins using an affinity purification followed by their proteomic identification, ii) map the H2O2 modified cysteins and validate their role in protein fonction and iii) characterise the role of the sulfenylation during the symbiotic interaction through a functional in planta analysis. The project aims at characterizing a completely new role for H2O2 as a signalling molecule in plants. The research programme will lead to the identification and the characterisation of H2O2-driven post-translational signalling. This will lead to important breakthroughs not only in the symbiotic field but also in compatible plant pathogen interaction and more generally of plant development. In this respect, it is expected to open new fields of investigation.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences biological sciences biological behavioural sciences ethology biological interactions
- agricultural sciences agriculture, forestry, and fisheries agriculture grains and oilseeds legumes
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2009-RG
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
75007 PARIS CEDEX 07
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.