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Content archived on 2024-06-18

Translation of Computational Heart Models into the Clinic

Objective

The main objective of ComHeart2Clinic is the integration of multi-scale computational models of the heart into the clinic, addressing the translational challenges of this research. The project is focused on the Cardiac Resynchronization Therapy – CRT, a treatment for Heart Failure. This therapy consists of the placement of three pacing leads in the heart of the patient to restore its synchrony. There is currently a rate of 30% of non-responders to CRT. Recent developments in heart computational models are providing promising tools that could increase CRT effectiveness, broaden inclusion criteria, maximize the CRT benefit and avoid unnecessary procedures. The research hypothesis is that such models will reduce the uncertainty of diagnosis and predict the response to CRT. The expected result is the development and validation of a “ComHeart-assisted CRT” system for an enhanced CRT clinical outcome by a better patient selection, lead position planning and pacemaker configuration. The project will address the personalization of the computational models, the system prototyping and the model verification & system validation.

Fields of science (EuroSciVoc)

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Call for proposal

FP7-PEOPLE-2009-RG
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Coordinator

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
EU contribution
€ 30 000,00
Address
WELLINGTON SQUARE UNIVERSITY OFFICES
OX1 2JD Oxford
United Kingdom

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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Linda Pialek (Ms.)
Links
Total cost
No data