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Functional genetic characterization of a mouse model of Glioma

Objective

There is a limited understanding of critical oncogenes and oncosuppressors of human brain tumors, which are often lethal within monthly frames. In order to better understand brain tumor homeostasis, we aim to apply unbiased functional genomics and synthetic lethality screenings to a mouse models of Glioma, and to validate such screenings using human Glioma cell lines. On the long term, this study may provide more effective prognostic factors and pharmacological targets for brain cancer treatment.

Call for proposal

FP7-PEOPLE-2009-IEF
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Coordinator

STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS
Address
Plesmanlaan 121
1066 CX Amsterdam
Netherlands

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Activity type
Research Organisations
Administrative Contact
Henri Van Luenen (Dr.)
EU contribution
€ 161 248,80