Objective
Chemistry has made major contributions towards fighting cancer (Europe's major cause of death) by developing small molecules which can act as anticancer drugs. But despite extensive research efforts, defeating cancer is proving to be an enormous challenge. Inorganic chemistry has made its most important contribution in the form of platinum (Pt) complexes, which provide highly effective chemotherapy for testicular, ovarian, neck, cervical and esophageal cancers. Drug resistance and toxic side effects means that there are many occasions when Pt-based treatment must be discontinued and limit the ability of Pt drugs to cure other forms of cancer such as the more common colon and breast cancers. The problem is that the drugs are not ‘smart’ – they are not capable of identifying cancer cells and they react with a wide range of molecules. Another significant limitation is that it is not possible to control when and where they exert cytotoxicity. Here we propose a novel methodology to make: 1) Pt complexes capable of identifying cancer cells, 2) Pt drugs with a built-in security device –a switch which we can turn on externally to make the Pt drug active only when it reaches the tumour.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences chemical sciences inorganic chemistry transition metals
- medical and health sciences basic medicine pharmacology and pharmacy drug resistance
- engineering and technology nanotechnology nano-materials nanocrystals
- medical and health sciences clinical medicine oncology breast cancer
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2009-IEF
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
EH8 9YL Edinburgh
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.