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Content archived on 2024-06-18

Developing Chiral Isothioureas as Asymmetric Organocatalysts; Synthesis, Catalysis and Mechanistic Investigations

Objective

Nucleophilic or Lewis-base catalysis encompasses a multitude of different catalyst types and reactions. Despite intense interest within this field, there still exists a need to develop novel small molecule catalyst architectures that display high catalytic efficiency and enantioselectivity in a range of C-C bond forming reactions. This project is concerned with the design, synthesis and validation of a range of chiral catalysts based upon the isothiourea architecture as Lewis bases. Building upon established precedent, materials will be designed that possess exceptional catalytic properties that will enable new asymmetric processes to be delineated. A full mechanistic evaluation of these catalysts will be completed, and applications of the optimised catalysts to carbocycle, heterocycle and natural product synthesis established. This project is of relevance to the Work Programme as it has the potential to generate excellent science and exceptional training for the Fellow that will help to contribute towards Europe’s scientific output and competitiveness. Furthermore, the professional development of the fellow will also be established, ensuring that she is well placed for re-integration with her chosen career path after the end of this fellowship.

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-PEOPLE-2009-IEF
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-IEF - Intra-European Fellowships (IEF)

Coordinator

THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS
EU contribution
€ 173 240,80
Address
NORTH STREET 66 COLLEGE GATE
KY16 9AJ ST ANDREWS
United Kingdom

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Region
Scotland Eastern Scotland Clackmannanshire and Fife
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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