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Content archived on 2024-06-18

New Methodology for the Synthesis of Bioactive Pyrrolidines and Pyrrolidinones

Objective

The development of new and efficient methodology for the synthesis of privileged structures of biological importance is an ever important goal for organic chemists. Natural products continue to provide a source of such important chemical entities for the treatment of human diseases. In particular the pyrrolidine and pyrrolidinone motif are biologically privileged structures which are present in over 9000 natural products, many of which possess important biological activity. The aim of this proposal is to develop a range of new transition metal mediated and transition metal catalysed synthetic methodologies for the efficient synthesis of pyrrolidines and pyrrolidinones which will be applied to the total synthesis of a biologically important natural product which contains a lactone-pyrrolidinone as its core heterocyclic motif. The developed synthetic methodology will also be applicable to the synthesis of a wide range of biologically active natural product targets.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-PEOPLE-2009-IEF
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-IEF - Intra-European Fellowships (IEF)

Coordinator

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
EU contribution
€ 130 430,60
Address
WELLINGTON SQUARE UNIVERSITY OFFICES
OX1 2JD Oxford
United Kingdom

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Region
South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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