Objective Sequence-controlled polymerizations play a key role in Nature. Although formed from a rather modest library of monomers, sequence-defined macromolecules such as proteins or nucleic acids are largely responsible for the complexity and diversity of the biological world. By analogy, one may predict that synthetic sequence-defined polymers could play an important role in modern applied materials science. Paradoxically, very little effort has been spent within the last decades for developing sequence-specific polymerization methods.In this scientific context, the target of the present proposal is to develop new approaches for controlling macromolecular sequences. In particular, new possibilities for controlling comonomer sequences in standard synthetic processes such as chain-growth polymerizations (e.g. controlled radical polymerization) and step-growth polymerizations will be investigated. The strategies for controlling sequences will be principally chemical (e.g. controlled monomer insertion, organocatalysis, sequential monomer additions) but physical (e.g. confinement, transient monomer complexation) and eventually biochemical (e.g. biocatalysis) routes will be also considered.The essence of this project is indeed highly fundamental. Indeed, the control over polymer sequences remains one of the last holy grails in polymer science. Nevertheless, on a longer term, this research may be also extremely relevant for applications. Indeed, sequence-controlled polymers are most likely the key towards new generations of functional sub-nanometric materials. Fields of science natural sciencesbiological sciencesbiochemistrybiomoleculesnucleic acidsnatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsnatural scienceschemical sciencespolymer sciences Programme(s) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) ERC-SG-PE5 - ERC Starting Grant - Materials and Synthesis Call for proposal ERC-2010-StG_20091028 See other projects for this call Funding Scheme ERC-SG - ERC Starting Grant Host institution CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS EU contribution € 1 200 000,00 Address RUE MICHEL ANGE 3 75794 Paris France See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Principal investigator Jean-François André Victor Lutz (Dr.) Administrative Contact Gaelle Bujan (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Beneficiaries (1) Sort alphabetically Sort by EU Contribution Expand all Collapse all CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS France EU contribution € 1 200 000,00 Address RUE MICHEL ANGE 3 75794 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Principal investigator Jean-François André Victor Lutz (Dr.) Administrative Contact Gaelle Bujan (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data
