Objective
Optical spectroscopy of single plasmonic nanoparticles (NPs) has evolved into a recognized tool for nanoscopic sensing applications, using the sensitivity to the NP's environment,charge, size, shape, and proximity to other NPs. Here, I propose taking advantage of the nanoparticle s minuscule size approaching molecular dimensions in novel ways. Single particle plasmon sensors are in many ways the smallest possible giving unprecedented access to molecular events. The small size amplifies fluctuations by molecular events, allows massive parallel detection of analytes within tiny devices, and to monitor single nanoparticle formation and electrochemical surface reactions in real time.
The objective of this project is therefore to develop and explore single-particle plasmon spectroscopy as a novel tool to study such molecular processes. The objective will be reached by (1) building three new setups progressing far beyond current technology and increasing time resolution, spectral sensitivity, and parallelization capability many orders of magnitude, (2) synthesizing nanoparticles with optimal plasmon sensing properties, and (3) simulating plasmon properties to guide the experiments and understand the physics behind the observed phenomena. The single-particle plasmon spectroscopy technique will be applied in four scientific directions to demonstrate its potential: (4) analyzing distance fluctuations of particle pairs linked by (bio-)polymers, (5) recording coverage fluctuations of biomolecules bound to nanoparticles, (6) demonstrating parallel detection of many analytes in multiplexed microfluidic devices, and (7) following particle formation and chemical reactions in a single particle reactor .
Single-particle plasmon spectroscopy has the potential to provide a revolutionary new tool to study molecular processes and to become a major commercial analytical tool, especially for pharmaceutical research and development.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules
- natural sciences chemical sciences polymer sciences
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors
- engineering and technology nanotechnology nano-materials
- natural sciences physical sciences optics spectroscopy
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
ERC-2010-StG_20091028
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Host institution
55122 MAINZ
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.