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White Biotechnology for added value products from renewable plant polymers: Design of tailor-made biocatalysts and new industrial bioprocesses

Objetivo

Plant polymers are the main source of renewable materials in Earth. The use of biotechnology will permit to develop new routes for cellulose and lignin-based added value products, including speciality paper products and surfactants. The industrial utilization of cellulose includes pulps for the paper industry. However, its characteristics permits to use cellulose for speciality products whose potential is still to be fully investigated. Lignin is a heterogeneous aromatic polymer, highly recalcitrant towards degradation. Most industrial uses of cellulose require the previous removal of lignin, which is generally burnt at the mill. However, the chemical nature of lignin makes this polymer an interesting source of aromatic chemicals.

Oxidoreductases are involved in both lignin biosynthesis and biodegradation. Therefore, they have the highest potential for modification of lignocellulosic materials and isolated lignins. However, the natural enzymes are far to optimally operate under industrial conditions. Some oxidoreductases have been extensively investigated in terms of structure-function relationships. This will allow a new approach based on tuning their catalytic and operational properties using protein-engineering tools, such as forced evolution, and site-directed mutagenesis.

The applications of tailor-made enzymes will include among others:
i) increase of strength and other properties of cellulose fibres, and improve refining;
ii) production of lignin-free cellulose for high-quality products;
iii) production of lignin-based surfactants (as dispersants and nano-emulsifiers) and adhesives. In this way, the IP will contribute to maintain the EU leading position in the market of industrial biotechnology.

The potential impact is illustrated by the turnover of the EU Paper-Forest cluster that attains 400 000 million/year. In this way, the IP will contribute to transform a part of the EU chemical sector to more sustainable and eco-friendly manufacturing processes.

Convocatoria de propuestas

FP6-2004-NMP-NI-4
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Régimen de financiación

IP - Integrated Project

Coordinador

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Aportación de la UE
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Dirección
Serrano 117
MADRID
España

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Participantes (25)