AQUAPHAGE aims to the formation of a strong network for the development of phage therapy in aquaculture through a well balanced research staff exchange program. The platform for the implementation of this initiative is a common project focused on the identification and exploitation of phages specific for bacterial pathogens that constitute serious threats for both freshwater and marine aquaculture. The target bacteria are Listonella anguillarum and V. harveyi, pathogens of Mediterranean aquaculture species (European sea bass and gilthead sea bream), Flavobacterium psychrophilum, serious pathogen of trout and Aeromonas salmonicida, obligate bacterial pathogen of Atlantic salmon. The capacities and synergies of the partners will be exploited towards these goals. Aquaculture facilities owned by the partners can provide the necessary materials for the isolation of a wide variety of phages. Enzyme Biotechnology, Molecular Biology and Genomics will provide strong background information for the most efficient selection of lytic phages. Enhancement of lytic activity using bacterial strains from the collections of the participating institutes will lead to the development of a final product with increased efficacy against these pathogens. Modern bioindicator system will be used for the assessment of disease treatment impact on the environemnt. The formation of this research partnership with partners owing expertise and excellence in their field will provide possibilities for inter-disciplinary exchanges and will constitute a technological and scientific platform for further cooperation in the field of Phage Therapy in Aquaculture.
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