Objective
"The target of the present project is to fabricate large loading capacity, stimuli-responsive drug delivery nanodevices (DDNDs) with potential application in anticancer therapy. The proposed theme is central to People Programme for Career Development framed under FP7 within a research area which is truly at the cutting-edge and which is strongly interdisciplinary (materials, chemistry and nanoengineering). The proposed work falls directly under “The European Strategy for Nanotechnology and the Nanotechnology plan”. In particular, there are two themes under this Action Plan addressed by this proposal, e.g. Health and NMP (Nanosciences, nanotechnologies, materials and new production technologies). The proposal involves both materials preparation and drug loading/releasing processes. The DDNDs will be made in three steps. Firstly, magnetic Fe3O4 nanoparticles (NPs) are prepared. Then a decomposable FeOOH shell will be coated on the NPs. Finally, the above core-shell structures will again be coated by a layer of mesoporous silica forming core-double shell structure. The DDNDs with increased hollow volume will be obtained by the decomposition of the FeOOH inner shell. Thereafter, the drug loading and releasing will be done in two separated steps where the release can be triggered by a stimulus input, e.g. sharp pH change. All structures/devices obtained from these steps will be thoroughly characterised. The evaluation on the delivery efficiency and improvement on the fabrication process parameters will be made according to the characterisation results. In particular, the ‘zero-release’ before the stimuli input, the load maximization per DDND and the sustainability of the release once triggered will be the main aims to be achieved in the project. As fulfilled, all pre-set training objectives will be realised by the knowledge and competencies gained in the project and will definitely benefit to the candidate career development and mobility among the European Research Area."
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2010-IEF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
CB2 1TN CAMBRIDGE
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.