Objective
This project aims to understand RNA silencing pathways in plants using the unicellular alga Chlamydomonas reinhardtii as a model. The aim is to characterise the different modules in the RNA silencing pathways, the ways that they interact to form complex regulatory networks and the effect of these networks on growth and development. The initial approach will involve genetic and molecular characterisation of components in RNA silencing machinery. Having identified these components, I will then use different approaches to modify the different modules and assess their involvement in growth and progression of the algal life cycle. Chlamydomonas is an appropriate model because it has RNA silencing pathways that are simplified versions of those in higher plants, but in which there is still the potential for complexity given the existence of different types of pathways associated with suppression of gene expression at the RNA and chromatin level. In addition, because Chlamydomonas can be cultured synchronously, it is possible to carry out a system level analysis of regulatory networks: the extracts will represent the content of a single cell type at a defined stage of the cell cycle whereas with higher plants there are complications for this analysis associated with different cell types.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology phycology
- natural sciences biological sciences genetics RNA
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2010-IEF
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
CB2 1TN CAMBRIDGE
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.