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Content archived on 2024-06-18

Visualizing Molecular Structural Dynamics

Objective

Here, I seek funding to study the conformational dynamics of lipid bilayer fusion and electronic excitations in organic electronics, i.e. organic photovoltaic materials. I plan to use time-resolved wide angle X-ray scattering (WAXS) for these experiments, which I have developed funded by an Intra-European fellowship.

Direct observation of structural dynamics will have enormous impact in many natural sciences. Here I will demonstrate this using two examples.

(1) Fusion of cell membranes is central to life. It is important for endocytosis, viral infection, and its malfunction causes widespread diseases, such as Alzheimer or obesity. Despite its importance, the molecular mechanism of cell membrane fusion remains unproven. Time-resolved WAXS, as developed by myself, opens a unique experimental window to visualize the structural dynamics of the process. If successful, these experiments will significantly contribute to the understanding of the lipid bilayer fusion mechanism.

(2) Semiconducting polymers are currently actively investigated due to their potential use in electronic devices,. Using time-resolved WAXS, I propose to study the structural relaxation that key-polymers undergo when electronically excited. The study will shine new light onto the long-standing photophysical question about the nature and degree of structural relaxation of a molecular backbone when exposed to light. I also seek to visualize the structural relaxations in organic photovoltaic materials, which are thought to be performance limiting.

Combining my research experience prior and during the Intra-European fellowship, all experiments target fundamentally important scientific questions and each project will open a new experimental window to study molecular structural dynamics

Fields of science (EuroSciVoc)

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Topic(s)

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-PEOPLE-2010-RG
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-ERG - European Re-integration Grants (ERG)

Coordinator

GOETEBORGS UNIVERSITET
EU contribution
€ 45 000,00
Address
VASAPARKEN
405 30 Goeteborg
Sweden

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Region
Södra Sverige Västsverige Västra Götalands län
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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