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Content archived on 2024-05-30

Functional DNA-based nanomaterials using metal-mediated self-assembly processes

Objective

This research project will focus on the development of conducting molecular architectures using self-assembly processes between specific DNA sequences and metal ions-derivatives. The concept is to use the interaction of specific metal ions towards precise DNA nucleobases. Novel synthetic metal complexes will be prepared carrying specific functional units capable of directing the formation of conducting polymers. These metal complexes will be organized at the nanoscale by interaction with particular DNA base-sequences through self-assembly processes. The project will also involve the preparation of complex DNA-based nanomaterial structures through a novel route which extends upon the well-established DNA origami concept using the unique properties of metal ions and their specificity to form metal-mediated DNA duplexes. The self-assembly properties of DNA and specific metal-ions will be explored for the construction of complex nanoscale architectures. Importantly, the original methodology proposed will be also employed for the incorporation of further functionality into DNA-based nanomaterials, since the properties of the metal-complexes can be tailored with different functional groups.

Established synthetic methodologies will used for the synthesis of the metal-precursor compounds and these will be characterised using standard techniques to set up structural details, e.g. NMR, elemental analysis, ionized electrospray mass spectroscopy LC(IES-MS), spectroscopic (FTIR, UV-vis). The formation of conducting polymer nanomaterial will involve chemical oxidation or metal-coordination of the organized units along the DNA molecules. The resulting materials will be characterised using a range of spectroscopy techniques (FTIR, CD, UV-vis) as well as state-of-the-art scanning probe microscopy (AFM, EFM, STM). Finally, the conducting properties of the materials will be examined using a combination of 2-electrode devices and scanning probe methods.

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-PEOPLE-2010-RG
See other projects for this call

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-ERG - European Re-integration Grants (ERG)

Coordinator

UNIVERSIDAD DE GRANADA
EU contribution
€ 45 000,00
Address
CUESTA DEL HOSPICIO SN
18071 GRANADA
Spain

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Region
Sur Andalucía Granada
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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