European Commission logo
español español
CORDIS - Resultados de investigaciones de la UE
CORDIS

Activation of Hydrogen by Organic Frustrated Lewis Pairs. Applications in catalysis

Objetivo

Activation of H2 is typically a domain of transition metal catalysis -even nature uses metal-centred reactions for this process. However, very recently Stephan and Erker have described metal free systems able to activate dihydrogen by the use of Frustrated Lewis Pairs (FLP), a combination of sterically hindered Lewis acids and Lewis bases that for this geometric reason are not able to quench each other. Moreover they were able to apply these systems for the reduction of some imines using H2 directly instead of any organic surrogate.
Although this process is quite interesting, its applicability is nevertheless quite limited. Only silylenol ethers and very bulky imines can be satisfactorily reduced, non-encumbered ones simply react directly with B(C6F5)3, the ubiquitous Lewis acid used to form FLPs. To circumvent this obvious drawback I propose a new approach consisting in the use of completely organic molecules such as electron-poor allenes, alkenes, iminium salts and ketones as attractive alternatives to B(C6F5)3. The development of a totally organic FLP able to activate H2 reversibly goes far beyond the state-of-the-art as it is expected to allow the reduction of carbon-carbon and carbon-heteroatom double bonds without the use of any metal and employing directly H2. This wide-ranging extension of the FLP reactivity will clearly surpass classical metal catalysis in environmental issues as no noble metal will be necessary. Also, organocatalytic reductions will be outstripped in atom economy criteria as H2 and no heavier surrogate will be used as reducing agent.

Convocatoria de propuestas

ERC-2011-StG_20101014
Consulte otros proyectos de esta convocatoria

Régimen de financiación

ERC-SG - ERC Starting Grant

Institución de acogida

GEORG-AUGUST-UNIVERSITAT GOTTINGEN STIFTUNG OFFENTLICHEN RECHTS
Aportación de la UE
€ 485 447,30
Dirección
WILHELMSPLATZ 1
37073 Gottingen
Alemania

Ver en el mapa

Región
Niedersachsen Braunschweig Göttingen
Tipo de actividad
Higher or Secondary Education Establishments
Investigador principal
Manuel Alcarazo Velasco (Prof.)
Contacto administrativo
Nadja Daghbouche (Ms.)
Enlaces
Coste total
Sin datos

Beneficiarios (2)