Objective Modern lifestyle has dramatically changed the daily rhythms of life. Physical activity, diet and light exposure are no longer restricted to daytime hours, as technical and economical de-mands fuel the necessity to work outside usual working hours. Recent studies show that al-tered light exposure, shifted exercise patterns and untimely food intake following extended active periods into the night disturb the circadian clocks and severely disrupt endocrine and metabolic processes, contributing to an increased risk of type 2 diabetes/obesity. Especially shift workers constituting 20% of the European working population are affected by this prob-lem. Until now only few studies investigating circadian rhythm disturbances in the context of type 2 diabetes/obesity have been conducted in man. Within EuRhythDia a consortium of leading scientists supported by research-intensive SMEs aims to close this gap. The objective of the project is to achieve breakthroughs in the understanding of the causality between inner clock rhythm disturbances and the development of type 2 diabetes/obesity, and to verify whether re-setting the circadian clock through lifestyle interventions (exercise, diet, light exposure and melatonin intake) alters cardiometabolic risk to a clinically relevant degree. The project is based on shift workers as a model and combines genetic, epigenetic, proteomic, metabolomic, physiological, and clinical approaches. The consortium has direct access to well characterised human data incl. individuals predisposed to type 2 diabetes via LUPS co-hort. Additional small interventional and validation cohorts of shift workers and high risk juveniles will be recruited, and supportive animal studies will be conducted. Through the de-velopment of novel diagnostic assays enabling identification of patients at risk and elaboration of targeted prevention guidelines focusing on shift workers and juveniles, EuRhythDia will contribute to a positive impact on European citizens` health. Fields of science medical and health sciencesclinical medicineendocrinologydiabetesmedical and health scienceshealth sciencesnutritionobesity Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Topic(s) HEALTH.2011.2.4.3-3 - Molecular and physiological effects of lifestyle factors on diabetes/obesity Call for proposal FP7-HEALTH-2011-two-stage See other projects for this call Funding Scheme CP-FP - Small or medium-scale focused research project Coordinator UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF Address Martinistrasse 52 20251 Hamburg Germany See on map Region Hamburg Hamburg Hamburg Activity type Higher or Secondary Education Establishments Administrative Contact Rainer H. Böger (Prof.) Links Contact the organisation Opens in new window Website Opens in new window EU contribution € 1 575 228,80 Participants (16) Sort alphabetically Sort by EU Contribution Expand all Collapse all UNIVERSITAETSKLINIKUM AACHEN Germany EU contribution € 222 879,60 Address Pauwelsstrasse 30 52074 Aachen See on map Region Nordrhein-Westfalen Köln Städteregion Aachen Activity type Higher or Secondary Education Establishments Administrative Contact Volker Legewie (Mr.) Links Contact the organisation Opens in new window Website Opens in new window European ScreeningPort GmbH Participation ended Germany EU contribution € 374 685,26 Address Schnackenburgallee 22525 Hamburg See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Mira Grättinger (Dr.) Links Contact the organisation Opens in new window Website Opens in new window GENEDATA AG Switzerland EU contribution € 188 332,91 Address Margarethenstrasse 38 4053 Basel See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Timo Wittenberger (Dr.) Links Contact the organisation Opens in new window Website Opens in new window GERMEDIQ FORSCHUNGS-UND ENTWICKLUNGSGESELLSCHAFT MBH Participation ended Germany EU contribution € 0,00 Address Konig heinrich weg 48 22459 Hamburg See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Gerhild Böger (Dr.) Links Contact the organisation Opens in new window HELSINGIN YLIOPISTO Finland EU contribution € 179 704,40 Address Yliopistonkatu 3 00014 Helsingin yliopisto See on map Region Manner-Suomi Helsinki-Uusimaa Helsinki-Uusimaa Activity type Higher or Secondary Education Establishments Administrative Contact Sanna Leppämäki (Ms.) Links Contact the organisation Opens in new window Website Opens in new window FEDERATION INTERNATIONALE DU DIABETE REGION EUROPE AISBL Belgium EU contribution € 111 683,00 Address Avenue du bourgemestre etienne demunter 5b 1090 Bruxelles / brussel See on map Region Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad Activity type Other Administrative Contact Sophie Peresson (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITY OF LEEDS United Kingdom EU contribution € 705 100,00 Address Woodhouse lane LS2 9JT Leeds See on map Region Yorkshire and the Humber West Yorkshire Leeds Activity type Higher or Secondary Education Establishments Administrative Contact Martin Hamilton (Mr.) Links Contact the organisation Opens in new window Website Opens in new window ACADEMISCH ZIEKENHUIS LEIDEN Netherlands EU contribution € 152 501,60 Address Albinusdreef 2 2333 ZA Leiden See on map Region West-Nederland Zuid-Holland Agglomeratie Leiden en Bollenstreek Activity type Higher or Secondary Education Establishments Administrative Contact Linda Ouwerkerk (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Université Lille 2 Droit et Santé France EU contribution € 790 518,99 Address Rue paul duez 59000 Lille See on map Activity type Higher or Secondary Education Establishments Administrative Contact Marie Gompel (Dr.) Links Contact the organisation Opens in new window Website Opens in new window UCL Elizabeth Garrett Anderson Institute for Women’s Health Participation ended United Kingdom EU contribution € 198 793,00 Address Gower street WC1E 6BT London See on map Region London Inner London — West Camden and City of London Activity type Higher or Secondary Education Establishments Administrative Contact Greta Borg-Carbott (Ms.) Links Contact the organisation Opens in new window Website Opens in new window OUTSIDE IN (CAMBRIDGE) LTD United Kingdom EU contribution € 58 168,00 Address The links trafalgar way bar hill 3 CB23 8UD Cambridge See on map Region East of England East Anglia Cambridgeshire CC Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Jonathan Cridland (Mr.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITAETSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAET MAINZ Germany EU contribution € 124 800,00 Address Langenbeckstrasse 1 55131 Mainz See on map Region Rheinland-Pfalz Rheinhessen-Pfalz Mainz, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Administrative Contact Uta Veith (Dr.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA Italy EU contribution € 707 000,04 Address Via cracovia 50 00133 Roma See on map Region Centro (IT) Lazio Roma Activity type Higher or Secondary Education Establishments Administrative Contact Francesco Pallone (Prof.) Links Contact the organisation Opens in new window Website Opens in new window GEMEINNUTZIGE SALZBURGER LANDESKLINIKEN BETRIEBSGESELLSCHAFT Austria EU contribution € 262 200,00 Address Mullner hauptstrasse 48 5020 Salzburg See on map Region Westösterreich Salzburg Salzburg und Umgebung Activity type Other Administrative Contact Josef Niebauer (Prof.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITY OF SURREY United Kingdom EU contribution € 252 133,50 Address Stag hill GU2 7XH Guildford See on map Region South East (England) Surrey, East and West Sussex West Surrey Activity type Higher or Secondary Education Establishments Administrative Contact Maria Sega-Buhalis (Ms.) Links Contact the organisation Opens in new window Website Opens in new window FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV Germany EU contribution € 94 160,35 Address Hansastrasse 27c 80686 Munchen See on map Region Bayern Oberbayern München, Kreisfreie Stadt Activity type Research Organisations Administrative Contact Michael Prestele (Mr.) Links Contact the organisation Opens in new window Website Opens in new window
