Skip to main content

Preparedness, Prediction and Prevention of Emerging Zoonotic Viruses with Pandemic Potential using Multidisciplinary Approaches

Objective

The capacity of zoonotic RNA viruses to emerge as major agents of human disease can appear limitless. Current intervention strategies have demonstrated limited success. Rapid, innovative and effective solutions are needed to reduce the apparently accelerating process of zoonotic disease emergence. We will study the following zoonotic viruses with epidemic potential in Europe: influenza virus, hepatitis E virus, viruses of the Japanese encephalitis serocomplex and lyssaviruses. These diverse viruses arise from the main reservoirs and vectors of potentially emerging viral diseases and use the three major routes of transmission: respiratory, faecal-oral and vector borne. Inter-disciplinary studies will generate valuable data on patterns of crossing the species barrier, transmission and disease emergence, including ecological and anthropological factors which determine virus availability and opportunities for exposure and infection. We will unravel the complex biological interactions between the virus and the recipient hosts that drive the viral adaptation and elucidate the factors determining the ability of the viruses to spread to and between humans (including pandemic spread). Furthermore, immune mechanisms of protection and novel prevention strategies will be investigated. Data will be compiled in a unique and freely accessible data-sharing platform to build a framework for analysing the drivers of pathogen emergence. Modelling, building on the analysis of key data, will focus on the extent to which pathogen trajectories are predictable and will identify high-risk situations and environments. This will allow improvement of disease surveillance, control, preparedness and intervention. Training in leading European Universities, as well as exchanges of approaches and data sharing with national and international health organizations will strengthen European position in this global challenge.

Call for proposal

FP7-HEALTH-2011-two-stage
See other projects for this call

Coordinator

INSTITUT PASTEUR
Address
Rue Du Docteur Roux 25-28
75724 Paris Cedex 15
France
Activity type
Research Organisations
EU contribution
€ 3 201 554,22
Administrative Contact
Soizic Sergeant (Mrs.)

Participants (19)

ISTITUTO ZOOPROFILATTICO SPERIMENTALE DELLE VENEZIE
Italy
EU contribution
€ 1 014 017,84
Address
Viale Dell Universita 10
35020 Legnaro
Activity type
Other
Administrative Contact
Raffaella Testolin (Dr.)
KATHOLIEKE UNIVERSITEIT LEUVEN
Belgium
EU contribution
€ 794 361,77
Address
Oude Markt 13
3000 Leuven
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Monique Vanhaeren (Ms.)
UNIVERSITE D'AIX MARSEILLE
France
EU contribution
€ 693 772
Address
Boulevard Charles Livon 58
13284 Marseille
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Céline Damon (Ms.)
EIDGENOESSISCHES DEPARTEMENT DES INNERN
Switzerland
EU contribution
€ 984 745,60
Address
Inselgasse 1
3003 Bern
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Caroline De St. Simon
IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom
EU contribution
€ 876 316,70
Address
South Kensington Campus Exhibition Road
SW7 2AZ London
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Tatjana Palalic (Ms.)
AGENCE NATIONALE DE LA SECURITE SANITAIRE DE L ALIMENTATION DE L ENVIRONNEMENT ET DU TRAVAIL
France
EU contribution
€ 674 450
Address
14 Rue Pierre Et Marie Curie
94700 Maisons Alfort
Activity type
Research Organisations
Administrative Contact
Nicole Pavio (Dr.)
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Germany
EU contribution
€ 344 800
Address
Hofgartenstrasse 8
80539 Munchen
Activity type
Research Organisations
Administrative Contact
Thomas Lengauer (Prof.)
FUNDACIO INSTITUT D'INVESTIGACIO SANITARIA ILLES BALEARS

Participation ended

Spain
EU contribution
€ 93 706,21
Address
Carretera De Valldemossa, 79
07120 Palma
Activity type
Research Organisations
Administrative Contact
Monica Castresana (Ms.)
GOETEBORGS UNIVERSITET
Sweden
EU contribution
€ 483 160
Address
Vasaparken
405 30 Goeteborg
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Ellen Rydberg (Dr.)
PHILIPPS UNIVERSITAET MARBURG
Germany
EU contribution
€ 399 900
Address
Biegenstrasse 10
35037 Marburg
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Christian Veldman (Dr.)
ISTITUTO NAZIONALE PER LE MALATTIE INFETTIVE LAZZARO SPALLANZANI-ISTITUTO DI RICOVERO E CURA A CARATTERE SCIENTIFICO
Italy
EU contribution
€ 751 896
Address
Via Portuense, 292
00149 Roma
Activity type
Research Organisations
Administrative Contact
Giuseppe Ippolito (Dr.)
THE UNIVERSITY OF EDINBURGH
United Kingdom
EU contribution
€ 178 141,27
Address
Old College, South Bridge
EH8 9YL Edinburgh
Activity type
Higher or Secondary Education Establishments
Administrative Contact
David Dougal (Mr.)
ISTITUTO PER L'INTERSCAMBIO SCIENTIFICO
Italy
EU contribution
€ 328 943,15
Address
Via Chisola 5
10126 Torino
Activity type
Research Organisations
Administrative Contact
Roberto Palermo (Dr.)
Fondation Health Sciences e-Training
Switzerland
EU contribution
€ 151 252,25
Address
Place Saint-françois 1
1002 Lausanne
Activity type
Other
Administrative Contact
Jean-Pierre Kraehenbuhl (Prof.)
ISTITUTO SUPERIORE DI SANITA
Italy
EU contribution
€ 120 000
Address
Viale Regina Elena 299
00161 Roma
Activity type
Research Organisations
Administrative Contact
Rosa Maria Martoccia (Dr.)
ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA
Italy
EU contribution
€ 37 500
Address
Via Zamboni 33
40126 Bologna
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Luisa Romagnoli (Ms.)
UNIVERSITAT DE BARCELONA
Spain
EU contribution
€ 256 034,99
Address
Gran Via De Les Corts Catalanes 585
08007 Barcelona
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Xavier Gutiérrez (Mr.)
Freunde von GISAID e.V.
Germany
EU contribution
€ 373 800
Address
Lipowskystrasse 10
81373 Munchen
Activity type
Research Organisations
Administrative Contact
Jörg Paura (Dr.)
EIDGENOESSISCHES DEPARTEMENT FUER WIRTSCHAFT, BILDUNG UND FORSCHUNG
Switzerland
Address
Bundeshaus Ost
3003 Bern
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Caroline De St. Simon (Ms.)