Objective This interdisciplinary project aims to develop new statistical and machine learning approaches to analyze high-dimensional, structured and heterogeneous biological data. We focus on the cases where a relatively small number of samples are characterized by huge quantities of quantitative features, a common situation in large-scale genomic projects, but particularly challenging for statistical inference. In order to overcome the curse of dimension we propose to exploit the particular structures of the data, and encode prior biological knowledge in a unified, mathematically sound, and computationally efficient framework. These methodological development, both theoretical and practical, will be guided by and applied to the inference of predictive models and the detection of predictive factors for prognosis and drug response prediction in cancer. Fields of science medical and health sciencesclinical medicineoncologynatural sciencescomputer and information sciencesartificial intelligencemachine learning Programme(s) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) ERC-SG-PE6 - ERC Starting Grant - Computer science and informatics Call for proposal ERC-2011-StG_20101014 See other projects for this call Funding Scheme ERC-SG - ERC Starting Grant Coordinator ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS Address Boulevard saint michel 60 75272 Paris France See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Administrative Contact Sophie Cousin (Ms.) Principal investigator Jean-Philippe Vert (Mr.) Links Contact the organisation Opens in new window Website Opens in new window EU contribution No data Beneficiaries (1) Sort alphabetically Sort by EU Contribution Expand all Collapse all ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS France EU contribution € 1 496 004,00 Address Boulevard saint michel 60 75272 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Administrative Contact Sophie Cousin (Ms.) Principal investigator Jean-Philippe Vert (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data