Objective Core-shell materials are of enormous interest for many applications in nanotechnology and nanomedicine. Only recently, due to the achievements of the consortium, the generation of such nanoparticles by applying unique proteins from marine organisms has become possible. In this IAPP, based on a long-term and very successful cooperation between groups in Germany and Croatia, well known in the field of marine biotechnology of sponges and associated microorganisms, and now extended by an SME (NanotecMARIN GmbH) with a special focus on the exploitation of marine metal-oxide forming enzymes / proteins, a marine bacterial multicopper oxidase (MCO) and a sponge laccase, which are able to catalyze the oxidation of Mn(II) to Mn(IV), will be used to generate novel metal oxide nanocomposite materials. Enzymatically active MCO will be immobilized on magnetic iron oxide nanoparticles to enzymatically fabricate core-shell materials. In addition, MCO and laccase will be applied in combination with silica or other metal oxide-forming proteins (recombinant silicatein and silintaphin-1) to generate nanoparticles containing multiple shells of various materials, which can be doped with fluorescent dyes and proteins during their formation at mild conditions. These core-shell nanoparticles will be used in drug delivery, for removal of manganese or other heavy metals from contaminated aqueous solutions (remediation of contaminated environments), as well as for the development of antifouling strategies. Fields of science natural scienceschemical sciencesinorganic chemistryinorganic compoundsnatural scienceschemical scienceselectrochemistryelectrolysisnatural scienceschemical sciencesinorganic chemistrytransition metalsengineering and technologynanotechnologynano-materialsnatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsenzymes Programme(s) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) FP7-PEOPLE-2011-IAPP - Marie Curie Action: "Industry-Academia Partnerships and Pathways" Call for proposal FP7-PEOPLE-2011-IAPP See other projects for this call Funding Scheme MC-IAPP - Industry-Academia Partnerships and Pathways (IAPP) Coordinator UNIVERSITAETSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAET MAINZ Address Langenbeckstrasse 1 55131 Mainz Germany See on map Region Rheinland-Pfalz Rheinhessen-Pfalz Mainz, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Administrative Contact Werner E.G. Müller (Prof.) Links Contact the organisation Opens in new window Website Opens in new window EU contribution € 148 222,00 Participants (2) Sort alphabetically Sort by EU Contribution Expand all Collapse all RUDER BOSKOVIC INSTITUTE Croatia EU contribution € 297 296,00 Address Bijenicka cesta 54 10000 Zagreb See on map Region Hrvatska Grad Zagreb Grad Zagreb Activity type Research Organisations Administrative Contact Renato Batel (Prof.) Links Contact the organisation Opens in new window Website Opens in new window NANOTECMARIN GMBH Germany EU contribution € 410 504,00 Address Muhlstrasse 19 55218 Ingelheim am rhein See on map Region Rheinland-Pfalz Rheinhessen-Pfalz Mainz-Bingen Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Heinz C. Schröder (Prof.) Links Contact the organisation Opens in new window
