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Content archived on 2024-05-27

Marine nanobiotechnology: Manganese oxide-containing core-shell materials formed by proteins from marine organisms for biomedical and environmental applications

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Nanomaterials for health and environment

An EU-funded consortium is creating innovative metal oxide nanocomposite materials that have a wide range of applications. These range from facilitating the delivery of drugs to helping clean up the natural environment.

Industrial Technologies icon Industrial Technologies

Core-shell materials, where nanoparticles of a particular element are coated with another substance, can have many applications in nanotechnology and nanomedicine. A joint German and Croatian initiative has developed a process for applying unique proteins from marine organisms to nanoparticles to generate core-shell materials. The EU-funded CORESHELL project investigated the application of marine metal-oxide-forming enzymes and multicopper oxidase (MCO) enzymes from marine bacteria. It also focused on a form of laccase enzyme derived from marine sponges, which can be used to create metal oxide nanocomposite materials. Project partners immobilised a sponge laccase on magnetic iron oxide nanoparticles . In addition, the enzyme can be used together with silica or other metal-oxide-forming proteins to render nanoparticles containing multiple shells of metal oxides such as titania. The photocatalytic and ferromagnetic properties of the titania-iron oxide nanoparticles allowed the development of a method for fast and efficient elimination of bacteria applying a novel magnetic nanoparticle separator. Core-shell nanoparticles developed by the consortium will be used in the remediation of contaminated sites by removing bacteria and heavy metals. The nanoparticles can also be used for developing anti-fouling strategies.

Keywords

Nanomaterial, metal oxide, nanocomposite, core-shell material, multicopper oxidase, marine bacteria, laccase, iron oxide, anti-fouling

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