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Content archived on 2024-05-27

Development of Cytochrome P450 Enzymes for the Chemical Manufacturing Industries

Objective

The objective of the P4FIFTY project is to deliver a trans-European network of industrially oriented white biotechnologists fully trained in the application of cytochrome P450 monooxygenases (P450s) for application in the chemical manufacturing and pharmaceutical industries. This will
involve academic groups investigating P450 diversity exploration from the wild type enzymes and their genes, genome mining for novel P450s, the expression of these in suitable hosts, the enzymology and molecular biological manipulation of these (including directed evolution and high
throughput screening [HTS] methods), the chemical application and finally the chemical and biochemical engineering aspects of application. These inputs are supported by two industrial partners one from the pharmaceutical industries (drug metabolism and synthesis) and one from the large scale chemical manufacturing industry.

Call for proposal

FP7-PEOPLE-2011-ITN
See other projects for this call

Coordinator

UNIVERSITY OF YORK
EU contribution
€ 865 000,89
Address
HESLINGTON
YO10 5DD York North Yorkshire
United Kingdom

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Region
Yorkshire and the Humber North Yorkshire York
Activity type
Higher or Secondary Education Establishments
Administrative Contact
David Hudson (Mr.)
Links
Total cost
No data

Participants (9)