Objective
Nutrition during early development has an important impact on later health, particularly through greater obesity risk, as demonstrated by FP6 EARNEST. EarlyNutrition explores the current key hypotheses on likely causes and pathways to prevention of early life origins of obesity (specifically adiposity) and associated disorders. We bring extraordinary expertise and study populations of 470,000 individuals to investigate:
• The fuel mediated in utero hypothesis
• The accelerated postnatal weight gain hypothesis
• The mismatch hypothesis.
Scientific and technical expertise in placental biology, epigenetics and metabolomics will provide understanding at the cellular and molecular level, and refined strategies for intervention in pregnancy and early post natal life to prevent obesity.
Using existing cohort studies, ongoing and novel intervention studies and a basic science programme, we will provide the scientific foundations for evidence based recommendations for optimal EarlyNutrition that incorporate long-term health outcomes, focusing on 4 Target Groups: women before pregnancy; pregnant women; infants (incl. breastfeeding); young children.
Evidence is produced from animal and placental studies (Theme 1; T1), prospective cohort studies (T2), and randomised controlled trials in pregnant women and infants (T3). T4 covers scientific strategic integration, recommendation development and dissemination, including systematic reviews and behaviour change approaches.
A strong multi-disciplinary team of international leaders in the field including collaborators from USA and Australia achieves balance and complementarity.
The project’s impact comprises definitive evidence on early nutrition effects on health, enhanced EU and global policies, major economic benefits through obesity prevention and value-added nutritional products, and practical recommendations on optimal nutrition in Target Groups. Wide dissemination will be achieved through active engagement with stakeholders.
Field of science
- /medical and health sciences/health sciences/nutrition
- /medical and health sciences/clinical medicine/obstetrics and gynaecology/obstetrics
Call for proposal
FP7-KBBE-2011-5
See other projects for this call
Funding Scheme
CP-IP - Large-scale integrating projectCoordinator
80539 Muenchen
Germany
Participants (39)
WC2R 2LS London
8036 Graz
2300 Kobenhavn S
30003 Murcia
NG7 2RD Nottingham
0456 Oslo
4 Dublin
Participation ended
1081 HV Amsterdam
43003 Tarragona
2333 ZA Leiden
SO17 1BJ Southampton
3015 GD Rotterdam
18071 Granada
1165 Kobenhavn
02 091 Warszawa
CB2 1TN Cambridge
T12 YN60 Cork
20122 Milano
04730 Warszawa
10561 Athina
Participation ended
1050 Bruxelles
SE1 7EH London
2333 BZ Leiden
1030 Wien
Participation ended
6718 ZB Ede Gld
3584 CT Utrecht
68165 Mannheim
28050 Madride
94607 Oakland Ca
0248110 Wellesley Ma
78701 2982 Austin
44106 7037 Cleveland Ohio
6008 Subiaco
3052 Parkville
5005 Adelaide
4000 Liege
Participation ended
1081 HV Amsterdam
1081 HV Amsterdam
2333 BZ Leiden