Objective The project goal is to support the development of functional food ingredients and products that are beneficial for the human gut & immune system and therefore of crucial importance for quality of life. The project will study the effects of specific non-digestible polysaccharides which have shown health potential in this field. The health effects of NPS will be focused around enhancing immune defence against pathogens, the reduction of infectious diseases like common cold and influenza of elderly and will make use of EFSA supported biomarkers that enable immune function claims and underpin the mechanism involved. The studied mechanisms are the innate and adaptive immune system and the possible involvement of the microbiota and microbiota-mediated products. To achieve this goal new and existing NPS will be studied for their health effects in a systematic way by developing a toolbox of dedicated assays and models that can be used by industry and authorities to study and approve food ingredients with a similar health focus. The project will: 1) perform biochemical analyses to study compounds, effect of processing and bioavailability, 2) develop standardized in vitro screening methods to be able to predict in vivo effects, 3) use dedicated in vivo and ex vivo analyses to study mechanisms of action and to validate biomarkers and 4) use and validate this knowledge in an intervention study. By combining the knowledge that will be gained from molecular, cellular and whole-organism studies, the goal will be to understand the bioactive mechanisms of these NPS and use this knowledge to design functional food products. SMEs make a very large contribution to the project, both as beneficiary of the products and as a technology service provider related to health research. This proposed project should provide the scientific basis for international nutritional organisations to recommend an immune-related functional health claim for some of the NPS studied. Fields of science engineering and technologymaterials engineeringfibersmedical and health scienceshealth sciencesinfectious diseasesRNA virusesinfluenzamedical and health sciencesbasic medicineimmunologynatural sciencesbiological sciencesbiochemistrybiomoleculescarbohydrates Programme(s) FP7-KBBE - Specific Programme "Cooperation": Food, Agriculture and Biotechnology Topic(s) KBBE.2011.2.2-01 - Development of functional foods and ingredients Call for proposal FP7-KBBE-2011-5 See other projects for this call Funding Scheme CP-TP - Collaborative Project targeted to a special group (such as SMEs) Coordinator STICHTING WAGENINGEN RESEARCH Address Droevendaalsesteeg 4 6708 PB Wageningen Netherlands See on map Region Oost-Nederland Gelderland Veluwe Activity type Research Organisations Administrative Contact Jurriaan Mes (Dr.) Links Contact the organisation Opens in new window Website Opens in new window EU contribution No data Participants (16) Sort alphabetically Sort by EU Contribution Expand all Collapse all TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY Ireland EU contribution € 199 528,00 Address Oak park R93 Carlow See on map Region Ireland Southern South-East Activity type Higher or Secondary Education Establishments Administrative Contact Martin Cooney (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data NOFIMA AS Norway EU contribution € 440 844,00 Address Muninbakken 9-13 9291 Tromso See on map Region Norge Nord-Norge Troms og Finnmark Activity type Research Organisations Administrative Contact Anne Risbraathe (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT France EU contribution € 266 757,00 Address 147 rue de l'universite 75007 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Administrative Contact Emilie Briand-Dubreuil (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data INSTITUT PASTEUR France EU contribution € 97 440,00 Address Rue du docteur roux 25-28 75724 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Administrative Contact Nadia Khelef (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data CRC CLINICAL RESEARCH CENTER KIEL GMBH Germany EU contribution € 1 033 902,00 Address Schauenburgerstrasse 116 24118 Kiel See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Christiane Laue (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data BIOACTOR BV Netherlands EU contribution € 233 034,00 Address Oxfordlaan 70 6229 EV Maastricht See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Hans Van Der Saag (Mr.) Links Contact the organisation Opens in new window Other funding No data SWEDISH OAT FIBER AB Sweden EU contribution € 225 984,00 Address Bua hamn 6 43024 Varobacka See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Frédéric Prothon (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data GENETIC ANALYSIS AS Norway EU contribution € 328 509,00 Address Nycoveien 2 0485 Oslo See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Morten Isaksen (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data IMMITEC NORGE AS Norway EU contribution € 129 433,00 Address Farmannsveien 18-22 3111 Tonsberg See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Jan Oddvar Johansen (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data PRODIGEST Belgium EU contribution € 417 739,00 Address Technologiepark 3 9052 Gent zwijnaarde See on map Region Vlaams Gewest Prov. Oost-Vlaanderen Arr. Gent Administrative Contact Sam Possemiers (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data DE GROOT-WEEVERS PHILIPPUS JOSEPHUS Netherlands EU contribution € 88 377,00 Address Gunninglaan 70 7314NE Apeldoorn See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Philippus Josephus De Groot (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data WINCLOVE HOLDING BV Netherlands EU contribution € 92 800,00 Address Hulstweg 11 1032 LB Amsterdam See on map Region West-Nederland Noord-Holland Groot-Amsterdam Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Saskia Van Hemert (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data OREBRO UNIVERSITY Sweden EU contribution € 597 593,00 Address Fakultetsgatan 1 70182 Orebro See on map Region Östra Sverige Östra Mellansverige Örebro län Activity type Higher or Secondary Education Establishments Administrative Contact Ivarsson Ann-Britt (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data UNIVERSITY OF ABERDEEN United Kingdom EU contribution € 214 933,00 Address King's college regent walk AB24 3FX Aberdeen See on map Region Scotland North Eastern Scotland Aberdeen City and Aberdeenshire Activity type Higher or Secondary Education Establishments Administrative Contact Ian Tough (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data WAGENINGEN UNIVERSITY Netherlands EU contribution € 441 349,00 Address Droevendaalsesteeg 4 6708 PB Wageningen See on map Region Oost-Nederland Gelderland Veluwe Activity type Higher or Secondary Education Establishments Administrative Contact Jerry Wells (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA Italy EU contribution € 149 326,00 Address Via zamboni 33 40126 Bologna See on map Region Nord-Est Emilia-Romagna Bologna Activity type Higher or Secondary Education Establishments Administrative Contact Gastone Castellani (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data
