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Dietary Fibers supporting Gut and Immune Function - From polysaccharide compound to health claim

Objetivo

The project goal is to support the development of functional food ingredients and products that are beneficial for the human gut & immune system and therefore of crucial importance for quality of life. The project will study the effects of specific non-digestible polysaccharides which have shown health potential in this field. The health effects of NPS will be focused around enhancing immune defence against pathogens, the reduction of infectious diseases like common cold and influenza of elderly and will make use of EFSA supported biomarkers that enable immune function claims and underpin the mechanism involved. The studied mechanisms are the innate and adaptive immune system and the possible involvement of the microbiota and microbiota-mediated products. To achieve this goal new and existing NPS will be studied for their health effects in a systematic way by developing a toolbox of dedicated assays and models that can be used by industry and authorities to study and approve food ingredients with a similar health focus. The project will: 1) perform biochemical analyses to study compounds, effect of processing and bioavailability, 2) develop standardized in vitro screening methods to be able to predict in vivo effects, 3) use dedicated in vivo and ex vivo analyses to study mechanisms of action and to validate biomarkers and 4) use and validate this knowledge in an intervention study. By combining the knowledge that will be gained from molecular, cellular and whole-organism studies, the goal will be to understand the bioactive mechanisms of these NPS and use this knowledge to design functional food products. SMEs make a very large contribution to the project, both as beneficiary of the products and as a technology service provider related to health research. This proposed project should provide the scientific basis for international nutritional organisations to recommend an immune-related functional health claim for some of the NPS studied.

Convocatoria de propuestas

FP7-KBBE-2011-5
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Coordinador

STICHTING WAGENINGEN RESEARCH
Dirección
Droevendaalsesteeg 4
6708 PB Wageningen
Países Bajos
Tipo de actividad
Research Organisations
Aportación de la UE
€ 1 017 008
Contacto administrativo
Jurriaan Mes (Dr.)

Participantes (16)

TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY
Irlanda
Aportación de la UE
€ 199 528
Dirección
Oak Park
R93 Carlow
Tipo de actividad
Higher or Secondary Education Establishments
Contacto administrativo
Martin Cooney (Dr.)
NOFIMA AS
Noruega
Aportación de la UE
€ 440 844
Dirección
Muninbakken 9-13
9291 Tromso
Tipo de actividad
Research Organisations
Contacto administrativo
Anne Risbraathe (Ms.)
INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
Francia
Aportación de la UE
€ 266 757
Dirección
147 Rue De L'universite
75007 Paris Cedex 07
Tipo de actividad
Research Organisations
Contacto administrativo
Emilie Briand-Dubreuil (Ms.)
INSTITUT PASTEUR
Francia
Aportación de la UE
€ 97 440
Dirección
Rue Du Docteur Roux 25-28
75724 Paris Cedex 15
Tipo de actividad
Research Organisations
Contacto administrativo
Nadia Khelef (Dr.)
CRC CLINICAL RESEARCH CENTER KIEL GMBH
Alemania
Aportación de la UE
€ 1 033 902
Dirección
Schauenburgerstrasse 116
24118 Kiel
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contacto administrativo
Christiane Laue (Dr.)
BIOACTOR BV
Países Bajos
Aportación de la UE
€ 233 034
Dirección
Oxfordlaan 70
6229 EV Maastricht
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contacto administrativo
Hans Van Der Saag (Mr.)
SWEDISH OAT FIBER AB
Suecia
Aportación de la UE
€ 225 984
Dirección
Bua Hamn 6
43024 Varobacka
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contacto administrativo
Frédéric Prothon (Dr.)
GENETIC ANALYSIS AS
Noruega
Aportación de la UE
€ 328 509
Dirección
Nycoveien 2
0485 Oslo
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contacto administrativo
Morten Isaksen (Dr.)
IMMITEC NORGE AS
Noruega
Aportación de la UE
€ 129 433
Dirección
Farmannsveien 18-22
3111 Tonsberg
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contacto administrativo
Jan Oddvar Johansen (Mr.)
PRODIGEST
Bélgica
Aportación de la UE
€ 417 739
Dirección
Technologiepark 3
9052 Gent Zwijnaarde
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contacto administrativo
Sam Possemiers (Dr.)
DE GROOT-WEEVERS PHILIPPUS JOSEPHUS
Países Bajos
Aportación de la UE
€ 88 377
Dirección
Gunninglaan 70
7314NE Apeldoorn
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contacto administrativo
Philippus Josephus De Groot (Dr.)
WINCLOVE BIO INDUSTRIES BV
Países Bajos
Aportación de la UE
€ 92 800
Dirección
Hulstweg 11
1032 LB Amsterdam
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contacto administrativo
Saskia Van Hemert (Dr.)
OREBRO UNIVERSITY
Suecia
Aportación de la UE
€ 597 593
Dirección
Fakultetsgatan 1
70182 Orebro
Tipo de actividad
Higher or Secondary Education Establishments
Contacto administrativo
Ivarsson Ann-Britt (Ms.)
UNIVERSITY OF ABERDEEN
United Kingdom
Aportación de la UE
€ 214 933
Dirección
King's College Regent Walk
AB24 3FX Aberdeen
Tipo de actividad
Higher or Secondary Education Establishments
Contacto administrativo
Ian Tough (Mr.)
WAGENINGEN UNIVERSITY
Países Bajos
Aportación de la UE
€ 441 349
Dirección
Droevendaalsesteeg 4
6708 PB Wageningen
Tipo de actividad
Higher or Secondary Education Establishments
Contacto administrativo
Jerry Wells (Prof.)
ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA
Italia
Aportación de la UE
€ 149 326
Dirección
Via Zamboni 33
40126 Bologna
Tipo de actividad
Higher or Secondary Education Establishments
Contacto administrativo
Gastone Castellani (Prof.)