Objective "With over 3 million new cases and 1.5 million arising deaths each year in Europe, cancer is a major public health problem with an urgent need for new therapies. This proposal builds upon mounting evidence that ion channels and transporters underlie many of the hallmarks of cancer. Thus, proteins involved in membrane transport, long known as important drug targets in other pathologies (channelopathies), are a new class of therapeutic and/or diagnostic targets in oncology. IonTraC is first to propose a systematic analysis of the expression, function, as well as therapeutic and diagnostic potential of proteins involved in ion transport (the ""transportome"") in cancer. This paradigm will be implemented in pancreatic ductal adenocarcinoma (PDAC) which has one of the worst prognoses of all cancers, with an overall 5-year survival rate of less than 5%.IonTraC thereby provides the framework for an inter- and supra-disciplinary training for early stage researchers in a highly innovative, exponentially growing field in oncology which will have a major impact on other disciplines such as immunology and angiology as well.The main objectives of IonTraC are:• to provide a scientific and methodological platform for supra-disciplinary training of early stage researchers in and beyond the fields of ion transport and oncology• to provide an inter-sectoral training programme with special focus on career development of young researchers• to determine the concerted expression and function of ion channels and transporters required for the progression of PDAC, and• to provide validated therapeutic and diagnostic concepts and tools that are based on transport proteins serving as novel drug targets and/or biomarkers." Fields of science medical and health scienceshealth sciencespublic healthnatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsmedical and health sciencesclinical medicineangiologymedical and health sciencesbasic medicineimmunologymedical and health sciencesclinical medicineoncology Programme(s) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) FP7-PEOPLE-2011-ITN - Marie-Curie Action: "Initial Training Networks" Call for proposal FP7-PEOPLE-2011-ITN See other projects for this call Funding Scheme MC-ITN - Networks for Initial Training (ITN) Coordinator Westfälische Wilhelms-Universität Münster Address Schlossplatz 2 48149 Muenster Germany See on map Region Nordrhein-Westfalen Münster Münster, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Administrative Contact Ingo Niendorf (Mr.) Links Contact the organisation Opens in new window Website Opens in new window EU contribution No data Participants (9) Sort alphabetically Sort by EU Contribution Expand all Collapse all THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD United Kingdom EU contribution € 268 551,01 Address Wellington square university offices OX1 2JD Oxford See on map Region South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire Activity type Higher or Secondary Education Establishments Administrative Contact Stephen Conway (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data KOBENHAVNS UNIVERSITET Denmark EU contribution € 856 217,00 Address Norregade 10 1165 Kobenhavn See on map Region Danmark Hovedstaden Byen København Activity type Higher or Secondary Education Establishments Administrative Contact Ivan Kristoffersen (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data UNIVERSITA DEGLI STUDI DI BARI ALDO MORO Italy EU contribution € 253 112,00 Address Piazza umberto i 1 70121 Bari See on map Region Sud Puglia Bari Activity type Higher or Secondary Education Establishments Administrative Contact Vito Tritta (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE - LILLE I France EU contribution € 486 063,00 Address Cite scientifique 59655 Villeneuve d'ascq See on map Activity type Higher or Secondary Education Establishments Administrative Contact Martine Lecoutre (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data UNIVERSITA DEGLI STUDI DI FIRENZE Italy EU contribution € 254 454,00 Address Piazza san marco 4 50121 Florence See on map Region Centro (IT) Toscana Firenze Activity type Higher or Secondary Education Establishments Administrative Contact Mario Del Rosso (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE United Kingdom EU contribution € 268 551,01 Address South kensington campus exhibition road SW7 2AZ London See on map Region London Inner London — West Westminster Activity type Higher or Secondary Education Establishments Administrative Contact Brooke Alasya (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV Germany EU contribution € 462 390,00 Address Hofgartenstrasse 8 80539 Munchen See on map Region Bayern Oberbayern München, Kreisfreie Stadt Activity type Research Organisations Administrative Contact Dagmar Lange (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL Germany EU contribution € 233 695,01 Address Olshausenstrasse 40 24118 Kiel See on map Region Schleswig-Holstein Schleswig-Holstein Kiel, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Administrative Contact Susanne Neufeldt (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data Bayer Pharma AG Germany EU contribution € 233 695,00 Address Muellerstrasse 178 13353 Berlin See on map Region Berlin Berlin Berlin Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Delia Nölte (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data
