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Content archived on 2024-05-28

Modelling human ageing: developing and interrogating an integrated model of ageing to identify causal relationships between hormonal changes and gene expression changes

Objective

"Ageing has a profound impact on human society and modern medicine, yet it remains a major puzzle of biology. Both hormonal and gene expression changes have been implicated as causal mechanisms of ageing. It is not clear, however, which molecular or physiological changes are more important drivers of the process of ageing or how they influence each other. This project aims to develop and interrogate an integrated model of ageing to identify causal relationships between age-related changes at different biological levels. Specifically, this project aims to: 1) Build a mathematical model of age-related gene expression and hormonal changes with age; 2) Determine the causal relationship between these age-related changes using in silico analyses. 3) Develop a new model of ageing based on the results obtained to highlight the new causal relationships identified."

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-PEOPLE-2011-IEF
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-IEF - Intra-European Fellowships (IEF)

Coordinator

THE UNIVERSITY OF LIVERPOOL
EU contribution
€ 200 371,80
Address
BROWNLOW HILL 765 FOUNDATION BUILDING
L69 7ZX LIVERPOOL
United Kingdom

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Region
North West (England) Merseyside Liverpool
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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