Objective Diabetes mellitus, hypertension, obesity, hypercholesterolemia, smoking and physical inactivity are common in elderly persons and are all associated with an increased risk of myocardial infarction, stroke and dementia. Efficacious treatments of these cardiovascular diseases are available, but in elderly patients with multiple cardiovascular diseases and risk factors however, treatment is currently insufficient. Optimisation of management of these diseases in order to decrease the burden of cardiovascular disease and its long-term complications is urgently needed.In this project we will develop and evaluate an innovative intervention strategy to improve pharmacological and non-pharmacological treatment for cardiovascular disease in elderly patients. First, data from three large ongoing clinical trials on multi-component vascular interventions in the elderly will be used to explore efficacy and feasibility of various treatment regimens. Second, an innovative and interactive internet platform for self-management of vascular diseases in the elderly will be developed. Interactive support by practice nurses and patient’s own physician and monitoring of adverse events will be integrated. Third, the efficacy of access to this new internet platform will be evaluated in a randomised controlled trial in 2600 elderly with multiple cardiovascular diseases. Patients randomised to the control condition will receive regular care. Primary outcome is a composite score including three vascular risk factors: systolic blood pressure, LDL cholesterol and BMI. Secondary outcomes are new cardiovascular events, handicap, cognition and survival.This flexible internet-based intervention strategy can be easily translated and adapted for use in different health-care systems in the EU. It will allow for tailor-made interventions specifically suited to the needs of older people and meticulous monitoring of side effects. The expected decrease in new cardiovascular events and dementia will result in lowering of healthcare costs substantially. Fields of science natural sciencescomputer and information sciencesinternetmedical and health sciencesclinical medicineangiologyvascular diseasesmedical and health sciencesclinical medicineendocrinologydiabetesmedical and health sciencesbasic medicineneurologydementiamedical and health sciencesclinical medicinecardiologycardiovascular diseases Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Topic(s) HEALTH.2012.2.2.2-2 - Investigator-driven clinical trials for optimisation of management of elderly patients with multiple diseases Call for proposal FP7-HEALTH-2012-INNOVATION-1 See other projects for this call Funding Scheme CP-FP - Small or medium-scale focused research project Coordinator ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM EU contribution € 1 994 679,00 Address MEIBERGDREEF 15 1105AZ Amsterdam Netherlands See on map Region West-Nederland Noord-Holland Groot-Amsterdam Activity type Higher or Secondary Education Establishments Administrative Contact Rebecca Massonet (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (6) Sort alphabetically Sort by EU Contribution Expand all Collapse all VITALHEALTH SOFTWARE BV Netherlands EU contribution € 755 000,00 Address ZONNEOORDLAAN 17 6718 TK Ede Gld See on map Region Oost-Nederland Gelderland Veluwe Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Adriaan Van Der Heijden (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data KAROLINSKA INSTITUTET Sweden EU contribution € 416 860,00 Address Nobels Vag 5 17177 Stockholm See on map Region Östra Sverige Stockholm Stockholms län Activity type Higher or Secondary Education Establishments Administrative Contact Miles Davies (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data ITA-SUOMEN YLIOPISTO Finland EU contribution € 1 011 480,00 Address YLIOPISTONRANTA 8 70211 KUOPIO See on map Region Manner-Suomi Pohjois- ja Itä-Suomi Pohjois-Savo Activity type Higher or Secondary Education Establishments Administrative Contact Mari Tikkanen (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE France EU contribution € 1 227 480,00 Address RUE DE TOLBIAC 101 75654 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Administrative Contact Muriel Bouas (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data NOVAPTEN SARL France EU contribution € 323 920,00 Address RUE CHARLES V 14 75004 PARIS See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Yannick Meiller (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE United Kingdom EU contribution € 94 620,00 Address TRINITY LANE THE OLD SCHOOLS CB2 1TN Cambridge See on map Region East of England East Anglia Cambridgeshire CC Activity type Higher or Secondary Education Establishments Administrative Contact Renata Schaeffer (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data