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CORDIS

Benznidazol and Triazol REsearch group for Nanomedicine and Innovation on Chagas diseasE

Objective

The BERENICE consortium is aiming at providing a new and cost-effective solution to a better treatment for Chagas chronic patients. Please see its objectives below :

Main objective
• Obtain a more effective, better tolerated and cheaper formulation of a drug with trypanocidal activity to cure Chagas disease

Specific Objectives
• Obtain results of pharmacokinetics of new formulations
• Assess trypanocidal activity of new formulations in vitro and in animal model
• Involve partners, research and industry in endemic countries to promote technology transfer and promote in-site solutions at cheaper cost.
The foreseen results of this project would have firstly an impact on the better comprehension and control of the SUVs behavior as drug delivery nanodevices for the specific APIs to be conjugated. If this conjugation is successful, further impacts are expected dealing with technology transfer issues, such as scale-up of the corresponding SUVs preparation methodology and its implementation at industrial scale.
Apart from including stong participation from endemic countries's institutions, the consortium also involves private companies, thus enabling the participation of all the key actors of the chain to confront and control better Chagas disease. The innovative approach, through the new developed nano- and microparticles based formulations will have an important impact on the safety of the medicament since the therapeutic efficacy will increase and consequently the doses needed and the incidences caused by adverse effects will be reduced.

Call for proposal

FP7-HEALTH-2012-INNOVATION-1
See other projects for this call

Coordinator

INSTITUT CATALA DE LA SALUT
EU contribution
€ 1 092 805,17
Address
GRAN VIA DE LES CORTS CATALANES 587
08007 Barcelona
Spain

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Region
Este Cataluña Barcelona
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Joan X. Comella (Dr.)
Links
Total cost
No data

Participants (10)