Mid-Term Report Summary - SYNPHOS (Highly-Reactive (Regenerative) Phosphorus Building Blocks -<br/>New Concepts in Synthesis)
Since available phosphorus resources are declining, new ecological and economical processes are highly required. The worldwide reduction of available phosphorous resources urges a more thoughtful use of existing sources. However, unlike oil which is lost once it is used, phosphorus and phosphorous-compounds can be recovered and used over and over again or at least transformed into other P compounds of chemical use. The intention of the present research proposal is to contribute to the field of synthetic chemistry both, inorganic and organic, by identifying and developing highly-reactive phosphorus building blocks (SynPhos) that can be potentially regenerated. Despite the emphasis being currently on phosphorous, we were also able to demonstrate that this concept is not limited to phosphorous and phosphorous-compound but can also be applied to the higher congeners (As, Sb, Bi). Many of the phosphorous-based by-products from the chemical industry are regarded as waste, due to rather inert P-O or P-S bonds formed during the reaction. Key to success is therefore the transformation of resistant and unreactive P-O bonds (or P-S bond respectively) into more reactive P-N bonds, which are synthetically more useful.
Along this line a great deal of attention has been drawn to the synthesis and application of phosphorous-centered cations and frameworks bearing N-heterocyclic moieties.
In this context more efficient and environmentally benign processes could be established, which in principle combine the reuse of chemical compounds, the reduction of toxic waste and recycling of chemical reagents using our SynPhos reagents.
Along this line a great deal of attention has been drawn to the synthesis and application of phosphorous-centered cations and frameworks bearing N-heterocyclic moieties.
In this context more efficient and environmentally benign processes could be established, which in principle combine the reuse of chemical compounds, the reduction of toxic waste and recycling of chemical reagents using our SynPhos reagents.