Objective There is growing commercial interest in bio-responsive materials because of their many applications, such as in medicaldiagnostics at the point of care and in drug discovery and development. Our developed assay technologies manipulatethe properties of gold nanoparticles and enzyme-based reactions to detect enzyme activity. Most diagnostics target eitherexpressed antigens (immunodiagnostics) or DNA (molecular diagnostics).Our bio-responsive nanoparticle technology can offer a sensitive, specific and affordable platform for the development of rapidpoint-of-care tests based on simple colour readouts. Additionally one of the great advantages of our technology is the factthat, in addition to diagnosing disease, it can also potentially help in the search for new drugs to treat those diseases. Incontrast to methods that simply measure enzyme concentration, our method actually measures enzyme activity. In this ERCPOC our expected outcomes include a number of important commercial milestones and technical developments to expandthe platform to other diseases and test its application in high throughput drug screening. This valuewill carry through in both licensing and spin-out, since these issues are fundamental to any business venture. Furthermore,we propose a balanced plan that includes technical research combined with commercial investigations and identificationof appropriate industrial partners. At the conclusion of this work, we will be in a much stronger position to immediatelycommercialise this technology, bringing its benefits to the broader healthcare market. Fields of science medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsnatural sciencesbiological sciencesgeneticsDNAengineering and technologymedical engineeringmedical laboratory technologydiagnostic technologies Programme(s) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) ERC-OA-2011-PoC - European Research Council ERC Proof of Concept Call for proposal ERC-2011-PoC See other projects for this call Funding Scheme CSA-SA(POC) - Supporting action (Proof of Concept) Coordinator IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE Address South kensington campus exhibition road SW7 2AZ London United Kingdom See on map Region London Inner London — West Westminster Activity type Higher or Secondary Education Establishments Administrative Contact Shaun Power (Mr.) Links Contact the organisation Opens in new window Website Opens in new window EU contribution No data Beneficiaries (1) Sort alphabetically Sort by EU Contribution Expand all Collapse all IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE United Kingdom EU contribution € 147 918,00 Address South kensington campus exhibition road SW7 2AZ London See on map Region London Inner London — West Westminster Activity type Higher or Secondary Education Establishments Administrative Contact Shaun Power (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data
