Objective
In recent years, biomedical research has crossed international borders in large, collaborative studies showing the value of multidisciplinarity and scale advantage. This has yielded valuable insights and some led to new and better medicines and treatments for diseases. However, disease-focused studies provide less insight in the real disease onset, the relative disease burden in the population, and the actual comparability of selected patients. Large prospective cohort (LPC) studies following up initially healthy participants for years or decades are considered more reliable and different diseases can be studied. LPC studies require large numbers of subjects which are costly but particularly benefited from the advent of high throughput techniques providing opportunities for powerful study designs. This project unites the large study sets of the European Biobanking and Biomolecular Research Infrastructure (BBMRI) and the International Agency for Research on Cancer (IARC), thus achieving a worldwide unique scale of integration. Specifically, we aim to:1)Evaluate/improve the harmonization of individual data on health, lifestyle and other exposures;2)Develop/implement harmonized definitions of diseases;3)Improve biobanking and research technologies and develop innovative solutions facilitating high-quality, fair access to samples and data;4)Provide free transnational access by users, through study proposals selected by an open, pan-European call;5)In the framework of these studies, generate and provide access to whole genome sequences, transcriptome, proteome, metabolome and methylome data;6)Build new public-private partnerships involving large-scale prospective cohorts, and strengthening existing ones, allowing transparent industrial access to academic expertise;7) Build a network transferring the expertise of established European large-scale biobanks to new biobank initiatives under development in other countries.
Fields of science
Call for proposal
FP7-INFRASTRUCTURES-2012-1-RTD
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Funding Scheme
CP-CSA-Infra - Combination of CP and CSACoordinator
00014 Helsingin Yliopisto
Finland
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Participants (33)
2333 ZA Leiden
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69007 Lyon 7eme
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SW7 2AZ London
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8010 Graz
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17177 Stockholm
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NW1 2BE London
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9713 GZ Groningen
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85764 Neuherberg
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7491 Trondheim
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51005 Tartu
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751 05 Uppsala
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Participation ended
08028 Barcelona
CB22 3AT Cambridge
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7622 Pecs
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Participation ended
LE1 7RH Leicester
H3H 2R9 Montreal
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2111 XS Aerdenhout
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101 Reykjavik
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00271 Helsinki
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69006 Lyon
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1067 Riga
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21000 Split
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54 066 Wroclaw
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81675 Muenchen
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75654 Paris
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6200 MD Maastricht
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0456 Oslo
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2300 Kobenhavn S
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BS8 1QU Bristol
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8010 Graz
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20126 Milano
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08003 Barcelona
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