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Peroxisomes: key to cell performance and health

Objective

The PERFUME (PERoxisome Formation, Function, MEtabolism) program is an interdisciplinary and intersectoral ITN providing state-of-the-art research training at the interface of medicine, plant and fungal biology. The PERFUME S&T specifically aims at unraveling the principles of peroxisome biology.
Peroxisomes have been discovered relatively recently (in 1954). Consequently, the level of understanding of their biology is relatively weak compared to the knowledge of other organelles. Despite their modest appearance, they are crucially important for cell vitality. Peroxisomes ubiquitously occur in eukaryotes, display an unprecedented versatility of functions and are essential in man. Recent findings indicate that improper functioning of peroxisomes contributes to ageing and age-related diseases. However, there are still major gaps in our current knowledge of peroxisome biology. PERFUME aims to fill these gaps by focusing on i) the identification of novel peroxisome functions, ii) in-depth understanding of the compartmentalization of functions in peroxisomes and iii) unraveling the principles of peroxisome proliferation.
Enhancing knowledge on these three themes is relevant for medicine, agriculture and biotechnology and demands directed analyses, which require the combined expertise from different disciplines and sectors that cut across historically separated fields. PERFUME brings together such a team comprising of top scientists from the fields of cell biology, biochemistry, genomics, proteomics, metabolomics, mathematical modeling, bioinformatics and protein structure analysis. Together, PERFUME shows maximal complementarity and synergy to warrant optimal training facilities for the participating students.

Field of science

  • /natural sciences/biological sciences/cell biology
  • /natural sciences/mathematics/applied mathematics/mathematical model
  • /agricultural sciences/agriculture, forestry, and fisheries
  • /agricultural sciences/agriculture, forestry, and fisheries/agriculture
  • /natural sciences/biological sciences/biochemistry
  • /natural sciences/biological sciences/biochemistry/biomolecules/proteins/proteomics

Call for proposal

FP7-PEOPLE-2012-ITN
See other projects for this call

Funding Scheme

MC-ITN - Networks for Initial Training (ITN)

Coordinator

RIJKSUNIVERSITEIT GRONINGEN
Address
Broerstraat 5
9712CP Groningen
Netherlands
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 802 676,63
Administrative Contact
Dick Veldhuis (Dr.)

Participants (11)

ACADEMISCH ZIEKENHUIS GRONINGEN
Netherlands
EU contribution
€ 247 861,46
Address
Hanzeplein 1
9713 GZ Groningen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Barbara M. Bakker (Dr.)
ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM
Netherlands
EU contribution
€ 484 722,92
Address
Meibergdreef 15
1105AZ Amsterdam
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Sylvia G. Georgiev (Ms.)
THE UNIVERSITY OF EXETER
United Kingdom
EU contribution
€ 296 056,64
Address
The Queen's Drive Northcote House
EX4 4QJ Exeter
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Enda Clarke (Dr.)
UNIVERSITETET I STAVANGER
Norway
EU contribution
€ 569 342,84
Address
Kjell Arholms Gate 41
4021 Stavanger
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Troels Jacobsen (Mr.)
RUHR-UNIVERSITAET BOCHUM
Germany
EU contribution
€ 455 137,76
Address
Universitaetsstrasse 150
44801 Bochum
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Ralf Erdmann (Prof.)
EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany
EU contribution
€ 370 878,53
Address
Meyerhofstrasse 1
69117 Heidelberg
Activity type
Research Organisations
Administrative Contact
Margret Fischer (Ms.)
RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG

Participation ended

Germany
Address
Seminarstrasse 2
69117 Heidelberg
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Damien Devos (Dr.)
Evitraproteoma AB

Participation ended

Sweden
Address
Box 23052
10435 Stockholm
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Maria Dollhopf (Dr.)
METABOLON GMBH
Germany
EU contribution
€ 235 374,15
Address
Am Muhlenberg 11
14476 Potsdam
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Nicolas Schauer (Dr.)
LIFEGLIMMER GMBH
Germany
EU contribution
€ 211 331,48
Address
Markelstrasse 38
12163 Berlin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Susanne Hollmann (Dr.)
UNIVERSIDAD PABLO DE OLAVIDE
Spain
EU contribution
€ 237 681,62
Address
Carretera De Utrera Km 1
41013 Sevilla
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Damien Devos (Prof.)