Objective
The purpose of this project is to improve sustainable control of onchocerciasis (river blindness) through refinement of existing chemotherapeutic regimes and identification of new targets and approaches for integrated control that will combine chemotherapy with vaccination.
The demand for these studies comes from:
1, the need to control re-emergence of onchocerciasis in regions where transmission had been interrupted;
2, indications consistent with the emergence of ivermectin resistance; and
3, concern about adverse side reactions following ivermectin treatment in loiasis endemic areas.
There are three primary objectives:
Workpackage 1, Refinement of existing chemotherapeutic regimes by use of doxycycline to complement ivermectin treatment and further screening of existing drugs;
Workpackage 2, Assessment of immunological sequelae of ivermectin intervention and their implications for improved control strategies; and
Workpackage 3, identification of new targets, including vaccine candidates and approaches for integrated control.
As doxycycline is already licensed for human use, combination therapy with ivermectin for selected indications (not mass treatment) will deliver short term impact while providing a framework for the longer term vision of integrated chemotherapy-vaccine control of onchocerciasis
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2004-INCO-DEV-3
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
EDINBURGH
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.