Project description
High-Tech Research Intensive SMEs in FET research
We propose to engineer and validate a novel random access three-dimensional two-photon (2P) laser scanning microscope which can simultaneously image three different brain regions in the three spatial dimensions (3x3D system), where each scanned volume can exceed cubic millimeters. Our 3x3D system, which allows the simultaneous recording of neuronal activity in multiple, functionally connected distant brain volumes, is essential for understanding distributed brain computations. As each site can be scanned with sub-millisecond temporal resolution in several hundred user defined locations, the activity of single neurons in neuronal microcircuits or even neuronal compartments such as dendrites or axons will be followed. Furthermore, by combining imaging with powerful genetic methods and 3D photo-activation, we will not only record from identified circuits but also map connectivity between regions. We will validate the capability of our 3x3D system by simultaneously performing retinal, lateral geniculate nucleus, and cortical 3D imaging and photo stimulation. No currently available technology is able to achieve such multi-region 3D recordings of neuronal activity, considering not only products on the market but scientific publications as well. In the long term, the project leader SME will release a high-value added product family to the world market based on the methods and results that are realized and validated during this project. Despite steep competition from overseas laboratories, the first single region 3D 2P brain imaging was invented in Europe. Now, having similarly heavy competition this project attempts to realize the first multi-region 3D 2P brain imaging microscope.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences neurobiology
- natural sciences physical sciences optics microscopy
- natural sciences physical sciences optics laser physics
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-ICT-2013-C
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
1087 BUDAPEST
Hungary
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.