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Content archived on 2024-05-29

Sensing Biosystems and their Dynamics in fluids with Organic Transistors

Objective

The vision of BIODOT is a hybrid bio-organic technology for transduction of dynamical phenomena of biosystems in-vitro. The device that will be developed is based on organic ultra thin film transistors integrated with microfluidics. It will respond to subtle changes of the electrostatic charge at the interface between the biosystem in the solution and the organic semiconductor. These changes are due, for instance, to the flow of ions, the adsorption and diffusion of charged or polarisable molecules, the motion of large biomolecules, the activity of cells grown on the organic semiconductor.

The transduction of the dynamical behaviour of:
a) peptides involved in neurological functions,
b) phospholipids and functional membranes,
c) neurons and glia cells will be demonstrated during the project.

The signal will be correlated with dynamical data from fluorescence and scanning probe microscopy, computer simulations and structural techniques at the micro- and nano-scales. The integration of neural cells into this technology will extend the scope of the project towards long-term applications in biomedicine. These and other aspects make BIODOT a project aimed to achieve breakthroughs with respect to the state-of-the-art.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP6-2004-NMP-TI-4
See other projects for this call

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

STREP - Specific Targeted Research Project

Coordinator

CONSIGLIO NAZIONALE DELLE RICERCHE
EU contribution
No data
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Participants (7)

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