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Content archived on 2024-06-18

Ruthenium Based Protein-Protein Interaction Inhibitor’s

Objective

In this research, the fellow (Jayapal Reddy Mallareddy) will synthesize novel cell permeable fluorescent ruthenium complexes and demonstrate their utility for perturbing biological processes. This fellowship will build on the fellows expertise in synthetic chemistry (particularly peptide synthesis) applied at the biological interface, together with Leeds’ expertise in the design and synthesis of cell permeable inhibitors of protein-protein interactions. The project will ultimately furnish cell permeable fluorescent small molecules designed to act as inhibitors of key protein-protein interactions involved in disease development and progression. Such inhibitors can be used as tool molecules to understand biological processes, as sensors for malfunctioning proteins and as the starting point for development of new molecular therapeutics thus impacting the competitiveness of the EU, and the quality of life of its citizens, by facilitating new strategies for diagnosing and treating disease.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-PEOPLE-2012-IEF
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-IEF - Intra-European Fellowships (IEF)

Coordinator

UNIVERSITY OF LEEDS
EU contribution
€ 221 606,40
Address
WOODHOUSE LANE
LS2 9JT Leeds
United Kingdom

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Region
Yorkshire and the Humber West Yorkshire Leeds
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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