Objective
Nanotechnology is a rapidly increasing area of industry providing new and innovative solutions into many industrial sectors. The challenge faced by policy makers and the scientific community is that very little is actually known about the health effects of nanoparticles. It is essential that reliable information should be gathered before these particles enter widespread use to avoid potential health problems induced by the exposure to workers and consumers.
The overall goal of this research project is t o characterize features of specific engineered nanoparticles, to the delineate levels of exposure in occupational environments, and to explore health effects of exposure to these particles. Exposure levels will be evaluated under laboratory conditions and in occupational environments. The particles will be characterized with respect to their size distribution, solubility, surface activity, and potential for agglomerate formation. Health effects to be studied include genotoxicity and inflammatory response s. Genotoxicity will be assessed in relevant pulmonary cells measuring DNA and chromosomal damage. Inflammatory responses will be evaluated by measuring alterations in the panorama of pulmonary inflammatory cells as well as expression of biochemical markers of inflammation, i.e. cytokines and chemokines in vivo. To assess the effects on the vasculature, the potential of nanoparticles to induce pro-inflammatory or prothrombotic effects in the microcirculation of experimental animals will be explored.
Assuring the safety of new nanomaterials will be a crucial prerequisite for successful promotion of nanotechnological innovations and their applications in the future. This research aims at creating a reliable and sound foundation for the assessment of safety of nanoparticles, and in this way to the project will have a significant impact on the European capability for conducting research and innovation in the area of nanotechnology.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine pneumology asthma
- natural sciences biological sciences genetics DNA
- natural sciences chemical sciences inorganic chemistry inorganic compounds
- engineering and technology nanotechnology nano-materials
- natural sciences biological sciences genetics chromosomes
You need to log in or register to use this function
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2004-NMP-TI-4
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
HELSINKI
Finland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.