Objective
The evolution of Life on Earth has resulted in three types of organisms: the eukaryotes (higher organisms) and two distinct types of prokaryotes: the bacteria and the more recently discovered archaea. The archaea constitute a crucial link in the evolution of the prokaryotic to the aukaryotic cell. The essential systems for the processing of genetic information (DNA>RNA>Protein) that are present in eukaryotes are very similar to their simpler counterparts in archaea, and differ substantially form those in bacteria. Hence, archaea are excellent model systems for studying replication, DNA repair, transcription and translation in higher organisms. The model archaeon Sulfolobus is a unique candidate for an integrated multi-disciplinary project. The proposed SOLAR project will generate new insight on the processing of genetic information, by (i) extending the set of key proteins (and non coding-RNAs) involved and elucidating their interactions in vivo and in vitro, (ii) unravelling novel molecular mechanisms, and (iii) determining the modes of regulation of the protein complexes involved. This will certainly provide fundamental insights into the evolution of these importent processes, and into the orgin of the eukaryotic cell. Moreover, since malfunctions of the information processing systems, or their control, can have a major impact on survival and proliferation of cells and organisms, SOLAR applicants have recently filed several patents on new findings about archaeal protein functions that can lead to improved diagnosis and treatment of human diseases including cancer; the SOLAR project is anticipated to further extend these very promising developments. The partners of the SOLAR consortium have been selected on the basis of both excellent track records and complementary expertise. As such, the proposed project provides a unique opportunity for training of young, talented, European scientists in cutting-edge post-genomic and biochemical technologies.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology bacteriology
- natural sciences biological sciences microbiology virology
- natural sciences biological sciences genetics DNA
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences computer and information sciences data science data processing
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2005-MOBILITY-1
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
WAGENINGEN
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.