Final Report Summary - PHYSPROT (Determining Physical Properties of Heterogeneous Protein Complexes in Small Volumes)
The PhysProt project delivered a fundamentally new way to study proteins in solution in their native environment. A particular focus was on the manner in which proteins interact with other proteins to generate function and prevent malfunction. Through application of these methods we have been able to advance our understanding of the natural protection mechanisms present inside a living cell to recognise and mitigate aberrant protein self-assembly which can cause sever diseases. .