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Content archived on 2024-05-29

Integrating research into development and ageing ('LifeSpan')

Objective

Although human ageing has many dimensions it is a biological process that we share with nearly all living organisms. Therefore, we must comprehend the broad principles of the biology of ageing. We address this at a time when many preconceptions about the ageing process, such as that it is an ineluctable part of our biology, are being challenged. In line with the continuous increase of our lifespan, ageing may be intrinsically far more malleable than previously thought.
Ageing can only be understood by considering the entire human life history. Our life span is determined by genetic, environmental and stochastic factors, and evidence suggests that early-life events determine the individual status at the end of life. Therefore, we aim to bridge research on development with research on ageing, and to integrate these two disciplines that do not have a tradition of close interaction. We will move to and fro between experiments in (in)vertebrate models and observations in humans to test effects detected in one species as candidate longevity mechanism in the other. This approach has only been marginally explored and has never been attempted in one collaborative effort.
Some of us have begun to probe this unexplored field of research, but fragmentation in Europe must be avoided. LifeSpan ensures the future framework of ageing research that allows the appropriate questions to be asked, using the most suitable organisms, and taking the appropriate experimental and observational approach. This can only be done effectively when the research groups in Europe have the proper expertise and carry out their research in an integrative manner, in terms of science, organisation, and of a common education programme. All participants excel in science including the expertise and resources necessary for this Network. Crucially then, LifeSpan will provide the essential framework to reach European scientific excellence by """"Integrating research into Development and Ageing""""."

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP6-2005-LIFESCIHEALTH-6
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

NoE - Network of Excellence

Coordinator

ACADEMISCH ZIEKENHUIS LEIDEN ACTING UNDER THE NAME LEIDEN UNIVERSITY MEDICAL CENTER
EU contribution
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Total cost

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Participants (16)

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