Objetivo
Infectious diseases continue to be a serious burden around the world, in both developing and industrialised countries.
The present reality is that public health and medical communities are inadequately prepared. We must do more to improve our ability to prevent, detect, and control emerging, as well as resurging, microbial threats to health.
The main objective of DIAGNOSIS is to contribute to the above need by developing a novel easy to use, low cost mostly non invasive biotechnological platform for infectious diseases detection. The challenging aim is to reach a short and efficient sample treatment implemented into existing and newly developed portable PCR laboratory for multiplex fluorescent pathogen detection. The concept will be proven on human critical pathogens but will be applicable also for animals, and plants pathogens. The concept will be applicable for samples taken from affected organisms as well as from food/feed and environments (water, air, soil etc.) and has an articulate impact for the biodefense research.
The S&T objectives include : i) new principles of nucleic acids sorption/desorption, ii) innovative concentrating methods and materials for the enrichment of viruses, micro-organisms and nucleic acids, iii) adaptation of the phosphoramidite chemistry to alternative fluorescence dyes in order to broaden the labelling assortment for multiplex PCR analyses, a portable non-dependent on external power supply PCR laboratory, and iv) the exemplary demonstration of the whole technological chain on three groups of human pathogens: the Mycobacterium complex, the periodontitis pathogens, and the causal agents of uro-genital diseases, completed by the diagnosis of main representatives of food- and air-born pathogens.
Ámbito científico (EuroSciVoc)
CORDIS clasifica los proyectos con EuroSciVoc, una taxonomía plurilingüe de ámbitos científicos, mediante un proceso semiautomático basado en técnicas de procesamiento del lenguaje natural.
CORDIS clasifica los proyectos con EuroSciVoc, una taxonomía plurilingüe de ámbitos científicos, mediante un proceso semiautomático basado en técnicas de procesamiento del lenguaje natural.
- ciencias médicas y de la saludciencias de la saludsalud pública y medio ambiental
- ciencias naturalesciencias biológicasbioquímicabiomoléculasácido nucleico
- ciencias naturalesciencias biológicasmicrobiologíavirología
- ciencias médicas y de la saludciencias de la saludenfermedad infecciosa
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Convocatoria de propuestas
FP6-2005-LIFESCIHEALTH-7
Consulte otros proyectos de esta convocatoria
Régimen de financiación
STREP - Specific Targeted Research ProjectCoordinador
HILGERTSHAUSEN
Alemania